G5035
粒细胞巨噬细胞集落刺激因子 人
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
GM-CSF 人
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Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
14.6 kDa
Impurities:
≤1.000 EU/μg
产品名称
粒细胞巨噬细胞集落刺激因子 人, GM-CSF, recombinant, expressed in E. coli, suitable for cell culture
biological source
human
Quality Level
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
≤0.1 ng/mL EC50
mol wt
14.6 kDa
packaging
pkg of 4X5 μg, pkg of 5 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
≤1.000 EU/μg
color
white
solubility
water: soluble 0.010 mL, clear, colorless
UniProt accession no.
storage temp.
−20°C
General description
基于蛋白质含量的包装尺寸
Biochem/physiol Actions
粒细胞-巨噬细胞集落刺激因子(GM-CSF)是一种粒细胞、巨噬细胞和嗜酸性粒细胞谱系中的细胞生长和分化因子。GM-CSF在极低浓度下刺激多潜能祖细胞集落形成，是造血祖细胞在所有分裂过程中存活和增殖的重要因素。 它还能刺激一些上皮细胞和破骨细胞的生长。GM-CSF由多种细胞类型（单核细胞、内皮细胞、T细胞、成纤维细胞、丝裂原刺激的B细胞和脂多糖刺激的巨噬细胞）产生。GM-CSF是一种含有128个氨基酸的单链糖蛋白，采用保守二硫键。 人类和小鼠GM-CSF共享约。序列同源性54%，不发生生物活性交叉反应。
Physical form
从 0.2μm 过滤的 10mM 柠檬酸钠溶液 (pH3.5) 中冻干。
Analysis Note
使用人 TF-1 细胞在培养物中检测人 GM-CSF 的增殖活性。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| G5035-4X5UG | 04061833632888 |
| G5035-5UG | 04061833632895 |