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G6013

L -还原型谷胱甘肽

Name: <SC>L </SC>-还原型谷胱甘肽
Brand: SIGMA

≥98.0%, suitable for cell culture, BioReagent

别名:

γ-L-谷酰基-L-半胱氨酰-甘氨酸, GSH

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关于此项目

线性分子式:

H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H

化学文摘社编号:

70-18-8

分子量:

307.32

NACRES:

NA.26

PubChem Substance ID:

24895241

UNSPSC Code:

12352209

EC Number:

200-725-4

MDL number:

MFCD00065939

Beilstein/REAXYS Number:

1729812

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属性

产品名称

L -还原型谷胱甘肽, suitable for cell culture, BioReagent, ≥98.0%, powder

product line

BioReagent

Quality Level

300

assay

≥98.0%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

192-195 °C (dec.) (lit.)

solubility

H₂O: 50 mg/mL

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

说明

Application

可在5-10 mM下用于从谷胱甘肽琼脂糖洗脱谷胱甘肽S-转移酶(GST)。

Biochem/physiol Actions

作为内源性抗氧化剂在减少细胞代谢和呼吸爆发期间生成的活性氧方面发挥重要作用。谷胱苷肽S-转移酶催化异生素、白三烯和其他亲电子分子生成谷胱苷肽硫醚。谷胱苷肽也和蛋白质半胱氨酸残基形成二硫键。经由这些机制，它会产生降低抗癌药功效的逆反效应(paradoxical effect)。

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

谷胱甘肽在细胞培养中的应用

本页深入介绍了三肽、谷胱甘肽和其他重要细胞培养组分如何影响用于生物制造异源蛋白（包括单克隆抗体）的无血清、无蛋白质和无动物蛋白的细胞培养系统性能。

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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G6013-25G	04061833638743
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G6013-5G	04061833638750