G6019
甘油醛-3-磷酸脱氢酶 来源于人类红细胞
lyophilized powder, 50-150 units/mg protein
别名:
D-甘油醛-3-磷酸:NAD+ 氧化还原酶（磷酸化）, GAPDH
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
50-150 units/mg protein
form
lyophilized powder
Quality Level
specific activity
50-150 units/mg protein
composition
Protein, 40-70% biuret
UniProt accession no.
foreign activity
3-Phosphoglyceric phosphokinase ≤2%
storage temp.
−20°C
Gene Information
human ... GAPDH(2597)
Biochem/physiol Actions
甘油醛-3-磷酸脱氢酶可催化甘油醛-3-磷酸转化为1,3-双磷酸甘油酸酯，这是糖酵解的一部分。它也被证明在凋亡的启动、转录激活和内质网向高尔基囊泡的穿梭中起作用<<<18,New>>>。
Physical form
含柠檬酸钠缓冲盐的冻干粉
Other Notes
在具有3-磷酸甘油酸磷酸激酶的偶联系统中，在 pH 7.6、25℃ 条件下，一单位每分钟可将 1.0μmole的3-磷酸甘油酯减少为D-甘油醛3-磷酸。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
Bing Fang et al.
Biochimie, 95(2), 251-257 (2012-09-27)
siRNA is promising in anti-tumor therapy. The main challenge is lack of tumor-specific intracellular delivery. In this study, a 6 amino acids peptide (A1) with high affinity for vascular endothelial growth factor receptor-1 (VEGFR1) was conjugated with a cell penetrating
Pablo Moreno-Acosta et al.
Anticancer research, 32(10), 4319-4325 (2012-10-13)
The aim of this study was to evaluate the predictive utility of Insulin-like growth factor-1 receptor (IGF1R), IGF1, IGF2, Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and of hemoglobin levels for tumor response to exclusive radiotherapy, in patients with locally advanced Human papillomavirus
Milan Jirků et al.
The Journal of eukaryotic microbiology, 59(6), 537-547 (2012-08-01)
Several new species of trypanosomatids (Euglenozoa, Kinetoplastea, Trypanosomatidae), isolated from the intestines of Neotropical insects (Heteroptera), were genotyped on the basis of spliced leader RNA, and also defined phylogenetically using gene sequences of small subunit ribosomal RNA and glycosomal glyceraldehyde
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| G6019-100UN | 04061833638767 |