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Merck
CN

G6657

(−)-倍儿茶酸

≥98% (HPLC)

别名:

(2S,3R)-2-(3,4,5-三羟基苯基)-3,4-二氢-1(2H)-苯并-3,5,7-三醇

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关于此项目

经验公式(希尔记法):
C15H14O7
化学文摘社编号:
分子量:
306.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
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Quality Level

assay

≥98% (HPLC)

solubility

H2O: 5 mg/mL (heat 2-10 min at 105C), alcohol: soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(O)c(O)c3

InChI

1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15+/m1/s1

InChI key

XMOCLSLCDHWDHP-DOMZBBRYSA-N

General description

(−)-没食子儿茶素是一种多酚化合物,是存在于绿茶Camellia sinensis中主要的儿茶素之一。

Application

(−)-没食子儿茶素作为参考标准品的应用实例:
  • 高效液相色谱鉴定菠萝(Ananas comosus)中的多酚化合物
  • 高效液相色谱/光电二极管阵列检测(RP-HPLC/PDAD)分析绿茶Camellia sinensis来源的儿茶素特征
  • 作为参考标准品,用于通过高效液相色谱-四极杆飞行时间串联质谱(HPLC-qTOF-MS/MS)分析圆叶葡萄(muscadine grape) 杂交种的黄烷-3-醇(黄烷醇)类化合物特征

Biochem/physiol Actions

(−)-没食子儿茶素(GC)具有清除自由基的抗氧化特性。它也可抑制破骨细胞生成。没食子儿茶素可激发大肠杆菌抵抗紫外线诱导突变的抗突变活性。它也可抑制牙龈卟啉单胞菌在口腔上皮细胞上的生长和粘附。

Other Notes

在绿茶中发现的多酚化合物。(−)-表没食子儿茶素的差向异构体。


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research


Q Guo et al.
Biochimica et biophysica acta, 1427(1), 13-23 (1999-03-20)
The purpose of this study is to examine the relationship between the free radical scavenging activities and the chemical structures of tea catechins ((-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin (EGC) and (-)-epicatechin (EC)) and their corresponding epimers ((-)-gallocatechin gallate (GCG), (-)-gallocatechin (GC)
Chun Hay Ko et al.
Journal of agricultural and food chemistry, 57(16), 7293-7297 (2009-08-06)
In this study, three tea catechins, epigallocatechin (EGC), gallocatechin (GC), and gallocatechin gallate (GCG), were investigated for their effects on bone metabolism. The effects of the tea catechins on bone formation were evaluated using cultured rat osteoblast-like osteosarcoma cell line
S Sakanaka et al.
Bioscience, biotechnology, and biochemistry, 60(5), 745-749 (1996-05-01)
Effects of polyphenolic compounds isolated from green tea (Camellia sinensis) on the growth and adherence of Porphyromonas gingivalis onto human buccal epithelial cells were investigated. Green tea polyphenols, especially (-)-epigallocatechin gallate (EGCg) which is a dominant component of tea polyphenols



全球贸易项目编号

货号GTIN
G6657-1MG04061833640395
G6657-5MG04061833640401