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Merck
CN

G9880

谷丙转氨酶 来源于猪心脏

ammonium sulfate suspension, ≥75 units/mg protein

别名:

ALT1, L-丙氨酸:2-酮戊二酸氨基转移酶, GPT, 丙氨酸氨基转移酶(催化浓度)

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关于此项目

化学文摘社编号:
NACRES:
NA.54
UNSPSC Code:
12352204
EC Number:
232-561-4
MDL number:
Beilstein/REAXYS Number:
3562140
Specific activity:
≥75 units/mg protein
Biological source:
Porcine heart
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biological source

Porcine heart

Quality Level

form

ammonium sulfate suspension

specific activity

≥75 units/mg protein

mol wt

42 kDa

foreign activity

L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%, glutamic-oxalacetic transaminase ≤0.05%

shipped in

wet ice

storage temp.

2-8°C

General description

研究领域:细胞信号传导
谷丙转氨酶(GPT)位于体内大多数细胞中,但在肝脏中的浓度最高。 哺乳动物体内存在两种GPT亚型,GPT1和GPT2。

Application

猪心谷丙转氨酶已用于测定聚乙二醇(PEG)水溶液中的L-乳酸水平。

Biochem/physiol Actions

GPT负责催化α-酮戊二酸和丙氨酸可逆地转氨化为谷氨酸和丙酮酸。它还在氨基酸代谢和糖异生中起关键作用。
谷丙转氨酶 (GPT) 存在于体内大多数细胞中,但在肝脏中浓度最高。由于在肝细胞坏死后 GPT 释放入血液,可作为肝脏疾病的标志物。

Physical form

1.8M (NH4)2SO4 溶液中的悬浮液,pH 6.0

Analysis Note

由缩二脲确定的蛋白质。

Other Notes

一个单位在37℃和pH 7.6,L-丙氨酸存在条件下将1.0μmole α酮戊二酸转化成L-谷氨酸。


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

低风险生物材料

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历史批次信息供参考:

分析证书(COA)

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商品

以硫酸铵悬浮液形式提供的酶的使用指南

Instructions for working with enzymes supplied as ammonium sulfate suspensions


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全球贸易项目编号

货号GTIN
G9880-1KU04061833650806
G9880-500UN04061833650813