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Merck
CN

H0536

Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

别名:

HGF Receptor (c-Met)

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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biological source

human

Quality Level

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.1-5 ng/mL

mol wt

calculated mol wt 129 kDa

packaging

pkg of 100 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... MET(4233)

Biochem/physiol Actions

Heterodimeric transmembrane glycoprotein with binding capacity for c-Met. Activation of this receptor has been correlated with induction of the Ras pathway.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing 5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to bind human HGF.

Other Notes

Extracellular domain of c-Met fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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相关内容


M Park et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(18), 6379-6383 (1987-09-01)
We isolated overlapping cDNA clones corresponding to the major MET protooncogene transcript. The cDNA nucleotide sequence contained an open reading frame of 1408 amino acids with features characteristic of the tyrosine kinase family of growth factor receptors. These features include



全球贸易项目编号

货号GTIN
H0536-100UG04061833663349