H2270
氢化可的松琥珀酸酯 钠盐
powder, BioReagent, suitable for cell culture
别名:
11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate 钠盐, 氢化可的松 21-半琥珀酸酯 钠盐
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关于此项目
经验公式（希尔记法）:
C25H33NaO8
化学文摘社编号:
分子量:
484.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
204-725-5
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥90% (HPLC)
biological source
synthetic (organic)
Quality Level
product line
BioReagent
assay
≥90% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]
InChI
1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
InChI key
HHZQLQREDATOBM-CODXZCKSSA-M
Gene Information
human ... NR3C1(2908)
General description
用于上皮和内皮贴壁细胞培养的氢化可的松。
Application
Hydrocortisone 21-hemisuccinate sodium salt has been used as a supplement in Dulbecco′s modified Eagle medium/nutrient mixture F-12 (DMEM F12) for culturing oral squamous cell carcinoma (OSCC) cell lines and immortalized cone photoreceptor cell line.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Manashi Priyadarshini et al.
Life sciences, 287, 120141-120141 (2021-11-15)
SARI (suppressor of activator protein (AP)-1, regulated by interferon (IFN) was identified as a novel tumor suppressor by applying subtraction hybridization to terminally differentiating human melanoma cells. The anti-tumor activity of SARI and the correlation between expression and cancer aggression
Guang Yang et al.
Theranostics, 9(24), 7345-7358 (2019-11-07)
Rationale: Hepatitis B virus (HBV) is a leading cause of liver diseases. HBV covalently closed circular DNA (cccDNA) is a critical obstacle of complete elimination by anti-HBV therapy. HBV cccDNA accumulates in nucleus as a chromatin-like cccDNA minichromosome assembled by
Eleonora Nucera et al.
European journal of endocrinology, 164(1), 139-140 (2010-10-22)
We present the case of a woman with 'empty sella syndrome' who experienced generalized urticaria after the administration of sodium succinate hydrocortisone in two episodes. The patient underwent an allergological evaluation (prick, intradermal, and patch tests) with hydrocortisone sodium succinate
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H2270-100MG | 04061833791967 |