H2508
马尿酸-Arg
carboxypeptidase substrate, chromogenic, ≥98% (TLC), powder
别名:
N-苯甲酰-Gly-Arg
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关于此项目
经验公式（希尔记法）:
C15H21N5O4
化学文摘社编号:
分子量:
335.36
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
212-015-1
MDL number:
产品名称
马尿酸-Arg, carboxypeptidase substrate
Quality Level
assay
≥98% (TLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
NC(=N)NCCC[C@H](NC(=O)CNC(=O)c1ccccc1)C(O)=O
InChI
1S/C15H21N5O4/c16-15(17)18-8-4-7-11(14(23)24)20-12(21)9-19-13(22)10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,19,22)(H,20,21)(H,23,24)(H4,16,17,18)/t11-/m0/s1
InChI key
GFLCPYUSPYXNBV-NSHDSACASA-N
General description
羧肽酶底物B 和羧肽酶N.
Application
Hippuryl-Arg 已被用作
- 来自谷斑皮蠹
- 的氨基肽酶、来自油橄榄果实蝇Gmelin 的外肽酶、来自毕赤酵母
- 的中肠的底物
Biochem/physiol Actions
Hippuryl-Arg 是羧肽酶 B 和氨肽酶的合成底物。羧肽酶作用于精氨酸和赖氨酸的 C 端。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Hidefumi Komura et al.
Microbiology and immunology, 46(2), 115-117 (2002-04-10)
Carboxypeptidases (CP) in plasma and sera serve as regulators of anaphylatoxins such as C3a and C5a. The activity of CP can be measured by determining hippuric acid after cleavage of the small synthetic substrate hippuryl-L-arginine. Although a colorimetric assay is
Expression, purification and characterization of porcine pancreatic Carboxypeptidase B from Pichia pastoris for the conversion of recombinant human insulin
Mansur M, et al.
Enzyme and Microbial Technology, 40(3), 476-480 (2007)
H Schweisfurth et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 21(10), 605-609 (1983-10-01)
Kininase I (carboxypeptidase N; EC 3.4.17.3) consists of carboxypeptidase N1 (CN1) and carboxypeptidase N2 (CN2); these two enzymes can be differentiated by their activities towards hippuryl-L-arginine and hippuryl-L-lysine, respectively. A spectrophotometric assay for both carboxypeptidases in human serum is described
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H2508-1G | 04061833792216 |
| H2508-100MG | 04061833792209 |
| H2508-250MG | 04061833792223 |
| H2508-500MG | 04061832917580 |