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Merck
CN

H2775

DL - 苏式 -β-羟基天冬氨酸

别名:

苏式 -2-氨基-3-羟基琥珀酸

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关于此项目

经验公式(希尔记法):
C4H7NO5
化学文摘社编号:
分子量:
149.10
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352106
NACRES:
NA.32
EC Number:
224-299-4
MDL number:
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Quality Level

storage temp.

−20°C

SMILES string

N[C@H]([C@@H](O)C(O)=O)C(O)=O

InChI

1S/C4H7NO5/c5-1(3(7)8)2(6)4(9)10/h1-2,6H,5H2,(H,7,8)(H,9,10)/t1-,2-/m1/s1

InChI key

YYLQUHNPNCGKJQ-JCYAYHJZSA-N

Gene Information

human ... GLUL(2752)
mouse ... GLUL(14645)

General description

DL -苏式-β-羟基天冬氨酸 (THA) 是一种谷氨酸摄取抑制剂。

Application

DL-苏氨酸-β-在插管 sprague dawley 大鼠中使用羟基天冬氨酸 (THA) 阻断谷氨酸盐转运。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nina Bionda et al.
Amino acids, 42(1), 285-293 (2010-11-18)
A simple and practical general synthetic protocol towards orthogonally protected tHyAsp derivatives fully compatible with Fmoc solid-phase peptide synthetic methodology is reported. Our approach includes enantioresolution of commercially available D: ,L: -tHyAsp racemic mixture by co-crystallization with L: -Lys, followed
Ewa Nagańska et al.
Folia neuropathologica, 48(1), 35-44 (2010-04-13)
Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body including nervous system. For last years its role as cytokine involved in many physiological processes out of the bone marrow has been suggested. Moreover, it plays a
Claudio Laurido et al.
TheScientificWorldJournal, 2012, 279147-279147 (2012-04-27)
N-methyl-D-aspartic acid receptor (NMDAr) activation requires the presence of D-serine, synthesized from L-serine by a pyridoxal 5'-phosphate-dependent serine racemase (SR). D-serine levels can be lowered by inhibiting the racemization of L-serine. L-serine-O-sulfate (LSOS) and L-erythro-3-hydroxyaspartate (LEHA), among others, have proven



全球贸易项目编号

货号GTIN
H2775-250MG04061833007396
H2775-50MG04061833007402