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Merck
CN

I1646

IL-3 human

≥97% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

别名:

hIL-3, IL-3

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥97% (HPLC and SDS-PAGE)
Form:
lyophilized powder
Mol wt:
15 kDa
Impurities:
≤0.1 EU/μg
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产品名称

白细胞介素-3 人, IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

human

Quality Level

recombinant

expressed in E. coli

assay

≥97% (HPLC and SDS-PAGE)

form

lyophilized powder

potency

≤1.0 ng/mL ED50/EC50

quality

endotoxin tested

mol wt

15 kDa

packaging

pkg of 10 and 50 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

≤0.1 EU/μg

UniProt accession no.

storage temp.

−20°C

Biochem/physiol Actions

白介素3(IL-3)是一种多功能蛋白,起初被称为克隆形成单位刺激活性(CFU-SA),由活化的T淋巴细胞产生。IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3已显示出可从琼脂悬浮的骨髓细胞诱导巨噬细胞、嗜中性粒细胞、肥大细胞和巨核细胞的克隆形成。IL-3也可与IL-2发生互作,以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。IL-3的其他同义词包括泛特异性造血素、多克隆刺激因子、肥大细胞生长因子、爆发促进活性、组胺生成细胞刺激因子、P细胞刺激因子和WEHI-3因子。
白细胞介素3是由活化的T淋巴细胞产生的一种多功能蛋白。 IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3还与IL-2相互作用,以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。

Physical form

无添加剂冻干。已经过0.2 μm滤器过滤。

Analysis Note

通过剂量依赖性刺激人TF-1细胞的增殖来测量生物活性。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

产生人诱导多能干细胞(iPSC)的干细胞重编程实验方案,包括基于病毒和非病毒RNA的方法。

Stem cell reprogramming protocols to generate human induced pluripotent stem cells (iPSCs) including viral and non-viral RNA based methods.

商品

Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.

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全球贸易项目编号

货号GTIN
I1646-10UG04061833847954
I1646-50UG04061833847961