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I2753

Inosine 3′:5′-cyclic monophosphate sodium salt

Name: Inosine 3&#8242;:5&#8242;-cyclic monophosphate sodium salt
Brand: SIGMA

≥98%, powder

别名:

cIMP

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关于此项目

线性分子式:

C₁₀H₁₀N₄O₇PNa

化学文摘社编号:

41092-64-2

分子量:

352.17

UNSPSC Code:

41106305

PubChem Substance ID:

24896007

NACRES:

NA.51

MDL number:

MFCD00057137

Assay:

≥98%

Form:

powder

Storage temp.:

−20°C

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属性

产品名称

Inosine 3′:5′-cyclic monophosphate sodium salt, ≥98%

Quality Level

200

assay

≥98%

form

powder

storage temp.

−20°C

SMILES string

[Na].OC1C2OP(O)(=O)OCC2OC1n3cnc4C(=O)N=CNc34

InChI

1S/C10H11N4O7P.Na.H/c15-6-7-4(1-19-22(17,18)21-7)20-10(6)14-3-13-5-8(14)11-2-12-9(5)16;;/h2-4,6-7,10,15H,1H2,(H,17,18)(H,11,12,16);;

InChI key

XIUBZBACWHALEW-UHFFFAOYSA-N

说明

Application

Inosine 3′:5′-cyclic monophosphate (cIMP) is used in studies that compare the substrate specificity and activity of cyclic purines, including the 3′,5′-cyclic monophosphates cAMP and cGMP.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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Allosteric activation of cGMP-specific, cGMP-binding phosphodiesterase (PDE5) by cGMP.

Daisuke Okada et al.

Biochemistry, 41(30), 9672-9679 (2002-07-24)

The effects of cGMP binding on the catalytic activity of cGMP-specific, cGMP-binding phosphodiesterase (PDE5) are unclear because cGMP interacts with both allosteric and catalytic sites specifically. We studied the effects of cGMP on the hydrolysis of a fluorescent substrate analogue

Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.

Adam K Jagielski et al.

Archives of biochemistry and biophysics, 404(2), 186-196 (2002-07-31)

The effects of extracellular purinergic agonists and their breakdown products on glucose and glutamine synthesis in rabbit kidney-cortex tubules incubated with aspartate + glycerol or alanine + glycerol + octanoate were investigated. A rapid extracellular degradation of ATP was accompanied

Stimulation of fluid secretion of malpighian tubules of drosophila melanogaster meig. by cyclic nucleotides of inosine, cytidine, thymidine and uridine

Riegel et al.

The Journal of experimental biology, 201 (Pt 24), 3411-3418 (1998-11-18)

External application of the 3',5'-cyclic monophosphates of inosine, cytidine, uridine and thymidine stimulated the fluid secretion rate (FSR) of Malpighian tubules isolated from Drosophila melanogaster. The evidence suggested that the cyclic nucleotides acted intracellularly in some capacity. Receptors of the

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全球贸易项目编号

货号	GTIN
I2753-1G	04061826691380
I2753-50MG	04061833007501