I2764
ML-7
≥98% (TLC), myosin light chain kinase inhibitor, powder
别名:
1-（5-碘萘-1-磺酰基）-1H - 六氢-1，4-二氮杂卓 盐酸盐
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关于此项目
经验公式（希尔记法）:
C15H17IN2O2S · HCl
化学文摘社编号:
分子量:
452.74
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
ML-7, powder
assay
≥98% (TLC)
Quality Level
form
powder
color
white
solubility
ethanol: water (1:1): 10 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
Cl.Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3
InChI
1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
InChI key
KDDALCDYHZIZMH-UHFFFAOYSA-N
Gene Information
human ... MYLK(4638), MYLK2(85366)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Iwona Bil-Lula et al.
Frontiers in bioscience (Landmark edition), 23, 298-309 (2017-09-21)
Matrix metalloproteinase-2 (MMP-2) mediated degradation of myosin light chain 1 (MLC1) and troponin I (TnI) contributes to myocardial ischemia/reperfusion (I/R) injury. Modifications of MLC1 triggered by oxidative stress are mediated by myosin light chain kinase (MLCK), nitric oxide synthase (NOS)
Ziad Al Nabhani et al.
Inflammatory bowel diseases, 23(7), 1109-1119 (2017-05-19)
Crohn's disease (CD) pathogenesis is multifactorial involving genetic and environmental factors. Loss of function mutations in the nucleotide oligomerization domain 2 (NOD2) gene are the main genetic risk factor for CD. Like patients with CD, Nod2 mice are characterized by
Zasp/Cypher internal ZM-motif containing fragments are sufficient to co-localize with alpha-actinin?Analysis of patient mutations
Klaavuniemi T and Ylanne J
Experimental Cell Research, 312(8), 1299-1311 (2006)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I2764-5MG | 04061833848647 |