产品名称
白介素1α 来源于大鼠, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
rat
Quality Level
recombinant
expressed in E. coli
assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
1-10 pg/mL ED50
quality
endotoxin tested
mol wt
~18 kDa
packaging
pkg of 5 μg
technique(s)
cell culture | mammalian: suitable
impurities
≤0.1 EU/μg
UniProt accession no.
storage temp.
−20°C
Gene Information
rat ... Il1a(24493)
Biochem/physiol Actions
白介素-1(IL-1),最初称为淋巴细胞激活因子(LA F),可激活T细胞和淋巴细胞,然后增殖并分泌白介素-2(L-2)。使用鼠细胞系D10S在培养物中检测人IL-1α的增殖活性。
Physical form
从含有0.25 mg牛血清白蛋白的0.2 μm过滤磷酸盐缓冲盐水中冻干。
Analysis Note
通过使用小鼠辅助T细胞系D10.G4.1刺激细胞增殖的能力来测量重组大鼠IL-1α的生物活性。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
含少量动物源组分生物产品
常规特殊物品
此项目有
商品
Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
Xuankang Wang et al.
Journal of neuroinflammation, 18(1), 256-256 (2021-11-07)
Neurotoxic microglia and astrocytes begin to activate and participate in pathological processes after spinal cord injury (SCI), subsequently causing severe secondary damage and affecting tissue repair. We have previously reported that photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation
T Nishida et al.
Journal of biochemistry, 105(3), 351-357 (1989-03-01)
A cDNA sequence coding for rat interleukin-1 alpha (IL-1 alpha) has been isolated from a cDNA library that was prepared with mRNA derived from LPS-stimulated rat peritoneal macrophages by using human IL-1 alpha cDNA as a probe. The rat cDNA
Aybike Saglam et al.
Glia, 69(4), 1022-1036 (2020-12-15)
Astrocytes are key players in CNS neuroinflammation and neuroregeneration that may help or hinder recovery, depending on the context of the injury. Although pro-inflammatory factors that promote astrocyte-mediated neurotoxicity have been shown to be secreted by reactive microglia, anti-inflammatory factors
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I3901-5UG | 04061833856437 |