I5125
肌醇 -肌醇
≥99% (GC), powder, precursor of membrane phospho-inositides and phospholipid
别名:
meso-肌醇, 环己六醇, 肌糖
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关于此项目
经验公式（希尔记法）:
C6H12O6
化学文摘社编号:
分子量:
180.16
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
201-781-2
MDL number:
Beilstein/REAXYS Number:
1907329
Assay:
≥99%
Quality level:
产品名称
肌醇 -肌醇, ≥99%
vapor density
6.2 (vs air)
Quality Level
assay
≥99%
mp
222-227 °C (lit.)
solubility
H2O: 50 mg/mL
SMILES string
O[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-
InChI key
CDAISMWEOUEBRE-GPIVLXJGSA-N
General description
肌醇（MI，myo-肌醇）是一种糖样分子，主要存在于人脑的神经胶质细胞中。它是C6糖醇的立体异构体，属于肌醇家族的一员。可作为三磷酸肌醇的前体，也可充当胞内第二信使。Myo-肌醇调节多种激素水平，如促甲状腺激素、促卵泡激素(FSH)和胰岛素。Myo-肌醇和d-chiro-肌醇（肌醇的另一种立体异构体）以不同方式平衡胰岛素抵抗(IR)有关的代谢异常。
Application
肌醇已用于：
- 作为气-液相色谱法（GC）单糖分析的标准品
- 作为无R海马培养基的组成部分，用于腹腔巨噬细胞（PMΦ）的培养，以研究细胞糖酵解代谢
- 作为SOFaaci培养基的补充，用于延长体外胚胎生长
- 作为α最低必需培养基（αMEM）完全培养基的组分，用于培养自然杀伤（NK）细胞系
Biochem/physiol Actions
肌醇（MI）作为渗透剂，是膜磷酸肌醇和磷脂的重要前体。它有助于形成细胞膜和髓鞘片结构。在阿尔茨海默症、脑胶质瘤病和脑肿瘤等各种脑部疾病中观察到肌醇（MI）浓度增加。
膜磷脂、糖基化磷脂酰肌醇锚定蛋白、磷酸肌醇酯第二信使的成分,其中锚定蛋白可将糖蛋白锚定到细胞膜上。
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I5125-100G | 04061835557332 |
| I5125-10MG | 04061835557349 |
| I5125-1KG | 04061835557356 |
| I5125-500G | 04061835557363 |
| I5125-50G | 04061835557370 |