biological source
human
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
assay
>95% (SDS-PAGE)
application(s)
research pathology
shipped in
dry ice
storage temp.
−20°C
General description
IgG抗体亚型是免疫系统中含量最高的血清免疫球蛋白。它由B细胞分泌，存在于血液和细胞外液中，可防止细菌、真菌和病毒引起的感染。母亲的IgG通过胎盘传递给胎儿，对于新生儿抗感染至关重要。IgG1是最丰富的IgG亚型
人骨髓瘤IgG1，κ从人血浆中通过分离，离子交换和亲和层析步骤纯化。
人骨髓瘤IgG1，κ从人血浆中通过分离，离子交换和亲和层析步骤纯化。
Application
纯化IgG1, κ可用作免疫球蛋白校对物，参考抗原，抑制剂或覆盖蛋白，用于各种免疫分析包括ELISA，点印迹免疫结合，Western免疫印迹，免疫扩散，免疫电泳，血凝反应和细胞结合分析。人骨髓瘤IgG1κ 被注入小鼠体内，用来评估T细胞和B细胞应答，还用于CHO细胞流式细胞仪。
Physical form
溶解在0.02M Tris缓冲液溶液，pH8.0。
Analysis Note
特性可以通过免疫电泳和非直接ELISA确定。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Johnny W Peterson et al.
Infection and immunity, 74(2), 1016-1024 (2006-01-24)
Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alternative treatment strategies are needed. We investigated whether a human monoclonal antibody (AVP-21D9) to protective antigen (PA) would protect mice, guinea pigs, and rabbits against anthrax. Control animals
Bas Cornelis Jansen et al.
PloS one, 13(7), e0200280-e0200280 (2018-07-07)
High-performance liquid chromatography (HPLC) is widely used for absolute quantitation. The advent of new columns and HPLC technology has enabled higher sample throughput, and hence, larger scale studies that perform quantitation on different sample types (e.g. healthy controls vs. patients
Yann Gallais et al.
Immunology and cell biology, 95(3), 306-315 (2016-10-08)
Patients treated with therapeutic biological products (BP) frequently develop anti-drug antibodies (ADA) with potential neutralizing capacities leading to loss of clinical response or serious side effects. BP aggregates have been suggested to promote immunogenicity, thus enhancing ADA production. Dendritic cells
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I5154-1MG | 04061833857175 |