I9646
IL-6 mouse
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
mIL-6, IL-6
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关于此项目
Biological source:
mouse
Recombinant:
expressed in E. coli
Assay:
≥97% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
~21.7 kDa
Impurities:
≤1.0EU/mg
产品名称
白介素 -6 来源于小鼠, IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free
biological source
mouse
Quality Level
recombinant
expressed in E. coli
assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
0.02-0.2 ng/mL EC50
quality
endotoxin tested
mol wt
~21.7 kDa
packaging
pkg of 5 and 25 μg
technique(s)
cell culture | mammalian: suitable
impurities
≤1.0EU/mg
color
white
UniProt accession no.
storage temp.
−20°C
Biochem/physiol Actions
白细胞介素-6 (IL-6) 是最初在双链 RNA 刺激的细胞培养基中发现的一种多功能蛋白。IL-6 似乎直接参与了感染和损伤后发生的反应，并可能证明在调节急性期反应方面与 IL-1 和 TNF-α同样重要。据报道，IL-6 由成纤维细胞、活化的 T 细胞、活化的单核细胞或巨噬细胞以及内皮细胞产生。作用于多种细胞，包括成纤维细胞、髓系祖细胞、T 细胞、B 细胞和肝细胞。如许多同义词所示，IL-6 诱导多种效应：浆细胞瘤生长因子 (PCT-GF)、干扰素-β-2（IFN-β 2 ）、单核细胞来源的人 B 细胞生长因子、B 细胞刺激因子 (BSF-2)、肝细胞刺激因子 (HSF)、白细胞介素杂交瘤/浆细胞瘤-1 (IL-HP1)。此外，IL-6 似乎在 T 淋巴细胞增殖中与 IL-2 相互作用。IL-6 还可增强 IL-3 对多潜能造血祖细胞的增殖作用。
Physical form
从不含添加剂的无菌过滤溶液中冻干。
Analysis Note
重组小鼠IL-6的生物学活性已通过使用T1165.85.2.1细胞经过细胞增殖试验进行测定。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I9646-25UG | 04061833865729 |
| I9646-5UG | 04061833865736 |