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关于此项目
经验公式(希尔记法):
C23H34O5
化学文摘社编号:
分子量:
390.51
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Quality level:
产品名称
Latanoprost acid, ≥95% (HPLC)
Quality Level
assay
≥95% (HPLC)
optical activity
[α]/D 26.0 to 36.0°, c = 0.1 in methanol
color
pale yellow, oil
solubility
DMSO: freely soluble, methanol: soluble
originator
Johnson & Johnson
shipped in
wet ice
storage temp.
−20°C
SMILES string
O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O)CCc2ccccc2
InChI
1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1
InChI key
HNPFPERDNWXAGS-NFVOFSAMSA-N
Gene Information
mouse ... Ptgfr(19220)
Biochem/physiol Actions
Potent, selective FP prostanoid receptor agonist, F-series prostaglandin analog. 200 times as potent as isopropyl ester form.
Features and Benefits
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Packaging
Store tightly sealed, under desiccant.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
商品
Discover Bioactive Small Molecules for Lipid Signaling Research
R N Weinreb et al.
Investigative ophthalmology & visual science, 38(13), 2772-2780 (1998-01-07)
To identify matrix metalloproteinases (MMPs) released by ciliary smooth muscle cells in vitro and to determine whether MMP release is altered by exposure to prostaglandins (PGs). Human ciliary smooth muscle cells were grown to confluence in monolayer cultures and treated
Rapid metabolic responses to prostaglandins in cultured cells expressing the FP-receptor.
E Walum et al.
Advances in experimental medicine and biology, 407, 231-236 (1997-01-01)
N Wang et al.
Current eye research, 22(3), 198-207 (2001-07-20)
Latanoprost, a prostaglandin F2a analogue and ocular hypotensive agent, alters extracellular matrix and matrix metalloproteinases (MMPs), including MMP-1, within tissues of the uveoscleral outflow pathway. In addition to these tissues, the anterior choroid also is exposed to fluid within the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L1292-5MG | 04061832785585 |
| L1292-1MG | 04061826675625 |