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关于此项目
经验公式(希尔记法):
C3H5LiO3
化学文摘社编号:
分子量:
96.01
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
248-692-5
Beilstein/REAXYS Number:
6127244
MDL number:
Quality Level
assay
≥98% (titration)
form
powder
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
<2% water (Karl Fischer)
color
white
solubility
water: 100 mg/mL, clear, colorless
cation traces
Li: 5.26-9.30% (anhydrous)
application(s)
food and beverages
hematology
microbiology
storage temp.
2-8°C
SMILES string
[Li+].C[C@H](O)C([O-])=O
InChI
1S/C3H6O3.Li/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1
InChI key
GKQWYZBANWAFMQ-DKWTVANSSA-M
General description
L-乳酸锂,也称为肌乳酸锂或 (S)-2-羟基丙酸锂,是 L-乳酸的锂盐,L-乳酸是乳酸的光学活性异构体,其特征在于 (S) 立体化学排列。L-乳酸是动物在正常代谢和运动过程中通过乳酸脱氢酶发酵丙酮酸而自然产生的。这种化合物是乳酸菌进行乳酸发酵的关键元素,其中碳水化合物被转化为乳酸。在人类中,乳酸及其共轭碱在各种生物过程中发挥着至关重要的作用,从产前发育到神经元周围细胞外液的维持。
最近的研究表明,L-乳酸锂具有稳定情绪的作用,特别是对于双相情感障碍患者。这种影响被认为与其对磷脂酰肌醇 (PI) 途径的影响和糖原合酶激酶 3 (GSK-3) 活性的抑制有关。除了双相情感障碍之外,正在进行的研究正在探索 L-乳酸锂在神经精神疾病中的潜在应用,包括与抑郁症、焦虑症和精神分裂症相关的研究,强调其在代谢组学和生化研究领域的重要性。
最近的研究表明,L-乳酸锂具有稳定情绪的作用,特别是对于双相情感障碍患者。这种影响被认为与其对磷脂酰肌醇 (PI) 途径的影响和糖原合酶激酶 3 (GSK-3) 活性的抑制有关。除了双相情感障碍之外,正在进行的研究正在探索 L-乳酸锂在神经精神疾病中的潜在应用,包括与抑郁症、焦虑症和精神分裂症相关的研究,强调其在代谢组学和生化研究领域的重要性。
Application
L-乳酸锂已用作一种标准品:
- 以通过分析方法测定乳酸含量
- 以通过高效液相色谱法测定乳酸含量
- 以用于L-乳酸的测定
L-乳酸锂是一种多功能化合物,可应用于代谢组学和生化研究。
Features and Benefits
- 非常适合代谢组学、生物学和生化研究
- 用途广泛,适用于各种实验室和研究应用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
实验方案
Quick and accurate analysis of D- and L-lactic acid in dairy products using Reflectoquant® Lactic Acid Test upon reaction with lactate dehydrogenase (LDH).
Rapid analysis of DL-lactic acid in vegan yogurt using the Reflectoquant® Lactic Acid Test, and enzymatic reaction with Lactate Dehydrogenase (LDH).
Nicolas Lebouvier et al.
Marine drugs, 7(4), 640-653 (2010-01-26)
As part of our search for new antimalarial drugs in South Pacific marine sponges, we have looked for inhibitors of Pfnek-1, a specific protein kinase of Plasmodium falciparum. On the basis of promising activity in a preliminary screening, the ethanolic
Akram Abouie Mehrizi et al.
Medical microbiology and immunology, 207(2), 151-166 (2018-02-06)
Malaria vaccine development has been confronted with various challenges such as poor immunogenicity of malaria vaccine candidate antigens, which is considered as the main challenge. However, this problem can be managed using appropriate formulations of antigens and adjuvants. Poly(I:C) is
Michael J McAnulty et al.
Biotechnology and bioengineering, 114(4), 852-861 (2016-11-02)
We previously demonstrated anaerobic conversion of the greenhouse gas methane into acetate using an engineered archaeon that produces methyl-coenzyme M reductase (Mcr) from unculturable microorganisms from a microbial mat in the Black Sea to create the first culturable prokaryote that
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