L4040
乳铁蛋白 人
recombinant, expressed in rice, Partially iron saturated, ≥90% (SDS-PAGE)
别名:
Growth-inhibiting protein 12, Lactotransferrin, Talalactoferrin
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关于此项目
Form:
powder
Assay:
≥70% protein basis (Bradford), ≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in rice
Application
使用乳铁蛋白在铁限制培养基中培养变形链球菌。 用于测试乳铁蛋白在体外是否阻碍上皮细胞黏附 。 同时用于测试血液细胞因子浓度对急性肺炎的诊断价值。
Biochem/physiol Actions
乳铁蛋白是一种铁结合蛋白。在结构上与血浆铁转运蛋白转铁蛋白相似；但是乳铁蛋白对铁的亲和力要高得多（250 倍）。在初乳中含量非常丰富，少量也可见于泪液、唾液、粘液分泌物和中性粒细胞的次级颗粒中。由粘膜上皮和中性粒细胞组成，在炎症刺激下由这些细胞释放。细菌的生长被其隔离铁的能力所抑制，也通过其 N 端与脂多糖结合使细菌细胞壁通透性增加。乳铁蛋白可以通过与病毒包膜蛋白紧密结合来抑制病毒感染。这通过阻断结合域阻止了细胞与病毒的融合。乳铁蛋白似乎部分通过刺激中性粒细胞激活剂白细胞介素-8 的释放来激活宿主防御系统。还可能参与抗体和白细胞介素合成、淋巴细胞增殖和补体激活。
Other Notes
rhLactoferrin manufactured in the USA by InVitria.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L4040-100MG | 04061833957233 |