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L4762

洛哌丁胺 盐酸盐

98-102% (USP), powder, Ca2+ channel blocker

别名:

4-（ p -氯苯基）-4-羟基- N,N -二甲基-α,α-二苯基-1-哌啶丁酰胺 盐酸盐

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关于此项目

经验公式（希尔记法）:
C29H33ClN2O2 · HCl
化学文摘社编号:
34552-83-5
分子量:
513.50
NACRES:
NA.77
PubChem Substance ID:
24278042
UNSPSC Code:
12352200
EC Number:
252-082-4
MDL number:
MFCD00058581
Quality level:
200
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产品名称

洛哌丁胺 盐酸盐,

Quality Level

200

originator

Johnson & Johnson

SMILES string

Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4

InChI

1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H

InChI key

PGYPOBZJRVSMDS-UHFFFAOYSA-N

Gene Information

human ... OPRM1(4988)

Application

盐酸洛哌丁胺 (HCl) 已用于炎性疼痛实验和评估蛋白质的功能性。54

Biochem/physiol Actions

盐酸洛哌丁胺 (HCl) 是一种非选择性 Ca 2 + 通道阻滞剂。在纳摩尔浓度下，与 μ-阿片受体。盐酸洛哌丁胺不能通过血脑屏障。

Features and Benefits

该化合物由 Johnson & Johnson 开发。如需浏览其他制药公司开发的化合物和批准的药物/候选药物列表，请点击此处。
这种化合物是ADME毒性研究的特色产品。点击此处发现更多特色ADME毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

Preparation Note

微溶于水和稀酸，易溶于甲醇和氯仿，可溶于95%乙醇。

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCF0872
0000089400
127M4884V
087M4769V
067M4887V

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全球贸易项目编号

货号GTIN
L4762-25G04061835546114
L4762-5G04061833957714