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L5647

利多卡因 盐酸盐 一水合物

≥99% (HPLC), solid, Na⁺ channel blocker

别名:

2-二乙氨基-N-（2，6-二甲苯基）乙酰胺 盐酸盐 一水合物, 利多卡因 盐酸盐 一水合物, 赛洛卡因 盐酸盐 一水合物

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关于此项目

经验公式（希尔记法）:
C14H22N2O · HCl · H2O
化学文摘社编号:
6108-05-0
分子量:
288.81
NACRES:
NA.77
PubChem Substance ID:
24277718
UNSPSC Code:
12352200
EC Number:
200-803-8
MDL number:
MFCD00150329
Form:
solid
Quality level:
200
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产品名称

利多卡因 盐酸盐 一水合物, solid

form

solid

Quality Level

200

color

white

solubility

H2O: soluble

SMILES string

Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2

InChI key

YECIFGHRMFEPJK-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

General description

Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.

Application

Lidocaine hydrochloride monohydrate has been used:
  • in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).
  • to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.
  • For inhibition of glial cells in brain tissue samples.

Biochem/physiol Actions

Na+ 通道阻滞剂；IB 类抗心律失常药，在肠胃外给药后迅速吸收
Na+ 通道阻滞剂；IB 类抗心律失常药。

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCJ3647
SLCF3130
SLBZ8366
SLBW4498
SLBR9987V

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Dubnika A, et al.
Ceramics International, 43(4), 3698-3705 (2017)
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Esposito G, et al.
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全球贸易项目编号

货号GTIN
L5647-100G04061835374762
L5647-15G04061833958339