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L5768

羊毛甾醇

Name: 羊毛甾醇
Brand: SIGMA

≥93%, powder

别名:

3β-羟基-8，24-羊毛二烯, 8，24-羊毛甾烷-3β-醇

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关于此项目

经验公式（希尔记法）:

C₃₀H₅₀O

化学文摘社编号:

79-63-0

分子量:

426.72

NACRES:

NA.77

PubChem Substance ID:

24896417

UNSPSC Code:

12352211

EC Number:

201-214-9

MDL number:

MFCD00021108

Assay:

≥93%

Form:

powder

Quality level:

200

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属性

Quality Level

200

assay

≥93%

form

powder

color

white to off-white

storage temp.

−20°C

SMILES string

[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](O)C(C)(C)[C@]4([H])CC3)[C@H](C)CC\C=C(/C)C

InChI

1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1

InChI key

CAHGCLMLTWQZNJ-BQNIITSRSA-N

说明

General description

羊毛甾醇作为一种两亲水脂分子，由羊毛甾醇合酶(LSS)产生，可在晶状体中富集。

Application

羊毛甾醇用于：

作为在HPLC在睾丸样本量化中的标准
用于S-腺苷-L-蛋氨酸：Δ²⁴-甾醇-C-甲基转移酶(SMT)分析
处理在丰富培养基中生长的野生型细胞，了解其对Sre1蛋白的影响

Biochem/physiol Actions

胆固醇前体甾醇。
羊毛甾醇用作巨噬细胞免疫的内源性选择性调节剂。

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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商品

胆固醇生物合成

胆固醇的生物合成通常发生在肝细胞的内质网中，并以乙酰辅酶A开始，乙酰辅酶A主要来源于线粒体中的氧化反应。乙酰辅酶A和乙酰乙酰辅酶A由HMG-辅酶A合成酶转化为3-羟基-3-甲基戊二酰辅酶A（HMG-辅酶A）。

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全球贸易项目编号

货号	GTIN
L5768-5MG	04061833958407
L5768-1MG	04061833958391