M0757
肉豆蔻酸异丙酯
≥90% (GC)
别名:
十四碳酸异丙酯, 十四酸异丙酯
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关于此项目
线性分子式:
CH3(CH2)12COOCH(CH3)2
化学文摘社编号:
分子量:
270.45
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-751-4
Beilstein/REAXYS Number:
1781127
MDL number:
biological source
synthetic (organic)
Quality Level
assay
≥90% (GC)
form
liquid
refractive index
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
density
0.85 g/mL at 25 °C (lit.)
functional group
ester
lipid type
saturated FAs
shipped in
ambient
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
Application
- Formulation design and development of matrix diffusion controlled transdermal drug delivery of glimepiride.: This study discusses the design of a transdermal drug delivery system for glimepiride, utilizing matrix diffusion mechanisms potentially incorporating Isopropyl Myristate to enhance permeation (Akram et al., 2018).
- Investigation of microemulsion and microemulsion gel formulations for dermal delivery of clotrimazole.: This article evaluates formulations incorporating Isopropyl Myristate for enhanced dermal delivery of clotrimazole, highlighting its role in improving drug solubility and skin absorption rates (Zhang and Michniak-Kohn, 2018).
Biochem/physiol Actions
Isopropyl myristate (myristic acid isopropyl ester) is used to change the physicochemical characteristics of microsheres such as poly(lactic-co-glycolic acid) (PLGA) microspheres. Isopropyl myristate is used as a oil phase component in the formulation of microemulsion systems.
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存储类别
10 - Combustible liquids
wgk
awg
flash_point_f
>302.0 °F
flash_point_c
> 150 °C
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Mahendra Singh et al.
Journal of controlled release : official journal of the Controlled Release Society, 328, 895-916 (2020-10-19)
The eye is the specialized part of the body and is comprised of numerous physiological ocular barriers that limit the drug absorption at the action site. Regardless of various efforts, efficient topical ophthalmic drug delivery remains unsolved, and thus, it
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M0757-1L | 04061838258403 |
| M0757-250ML | 04061838258410 |