产品名称
抗肌球蛋白(骨骼肌,快速)抗体,小鼠单克隆抗体, clone MY-32, purified from hybridoma cell culture
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MY-32, monoclonal
form
buffered aqueous solution
species reactivity
rat, chicken, rabbit, mouse, human, bovine, guinea pig, feline
packaging
antibody small pack of 25 μL
enhanced validation
independent
Learn more about Antibody Enhanced Validation
concentration
~1.0 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 10-20 μg/mL using porcine tongue, microarray: suitable, western blot: 0.5-1.0 μg/mL using total extract of rabbit skeletal muscle
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MYH1(4619), MYH2(4620)
mouse ... Myh1(17879), Myh2(17882)
rat ... Myh1(287408), Myh2(691644)
General description
定位于肌球蛋白重链上的表位。可对骨骼肌中发现的快速(II型)和新生儿肌动蛋白分子进行染色,但不会对培养细胞中的心肌、平滑肌或非肌肉肌球蛋白染色。能与人类横纹肌肉瘤发生反应。
Immunogen
兔肌肉肌球蛋白。
Application
使用单克隆小鼠抗肌球蛋白(骨骼/快速)作为一抗,以1:90000的稀释度,通过蛋白质印迹对来自具有过去损伤的运动员的血清样品中的肌球蛋白(快)水平进行测定。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
免疫组织化学(1篇论文)
免疫组织化学(1篇论文)
Physical form
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
低风险生物材料
常规特殊物品
此项目有
Yanlin Wang et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 40(6), 1255-1265 (2019-03-21)
Myotonic dystrophy type 1 (DM1) is caused by CTG nucleotide repeat expansions in the 3'-untranslated region (3'-UTR) of the dystrophia myotonica protein kinase (DMPK) gene. The expanded CTG repeats encode toxic CUG RNAs that cause disease, largely through RNA gain-of-function.
Charlotte Capitanchik et al.
Nucleus (Austin, Tex.), 9(1), 410-430 (2018-06-19)
Laminopathies yield tissue-specific pathologies, yet arise from mutation of ubiquitously-expressed genes. A little investigated hypothesis to explain this is that the mutated proteins or their partners have tissue-specific splice variants. To test this, we analyzed RNA-Seq datasets, finding novel isoforms
Tomohiko Akiyama et al.
Scientific reports, 8(1), 1189-1189 (2018-01-21)
Direct generation of skeletal muscle cells from human pluripotent stem cells (hPSCs) would be beneficial for drug testing, drug discovery, and disease modelling in vitro. Here we show a rapid and robust method to induce myogenic differentiation of hPSCs by
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M1570-200UL | 04061837720659 |
| M1570-100UL | 04061837720642 |