M5005
氯化锰 四水合物
BioReagent, suitable for insect cell culture
别名:
Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O
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关于此项目
线性分子式:
MnCl2 · 4H2O
化学文摘社编号:
分子量:
197.91
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
231-869-6
MDL number:
Assay:
≥99% (by AgNO3, titration)
product line
BioReagent
Quality Level
assay
≥99% (by AgNO3, titration)
technique(s)
cell culture | insect: suitable
mp
58 °C (lit.)
SMILES string
Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
InChI
1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
InChI key
CNFDGXZLMLFIJV-UHFFFAOYSA-L
Application
四水合氯化锰 (II) 已被用于：
- 作为真菌完全培养基中的微量元素
- 作为耳蜗器官型培养的培养基中的补充
- 测定其对小鼠单纯疱疹病毒-1 (HSV-1)、水泡性口炎病毒 (VSV) 和痘苗病毒的体内抗病毒活性
Biochem/physiol Actions
锰是哺乳动物组织中必需的和含量丰富的金属之一。在发育、神经元功能、免疫调节、生殖和抗氧化防御等生理过程中起关键作用。作为辅助因子，调节酶的活性，如氧化还原酶、异构酶、转移酶、连接酶、裂合酶和水解酶，参与固有免疫。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
target_organs
Brain
wgk
WGK 2
flash_point_f
does not flash
flash_point_c
does not flash
ppe
dust mask type N95 (US), Eyeshields, Gloves
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
manganese Increases the Sensitivity of the cgas-sting Pathway for Double-stranded Dna and Is Required for the Host Defense against Dna Viruses.
Wang C, et al.
Immunity, 48(4), 675-687 (2018)
Salidroside protects inner ear hair cells and spiral ganglion neurons from manganese exposure by regulating ROS levels and inhibiting Apoptosis
Ding X, et al.
Toxicology Letters, 310, 51-60 (2019)
Weilong Wang et al.
Toxicology letters, 279, 77-86 (2017-08-06)
Manganese (Mn) is an indispensable cofactor for many enzymes and a basic factor for many reproductive and metabolic pathways. However, exposure to high concentrations of Mn can result in deleterious effects on the central nervous system and peripheral nerves, including
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M5005-100G | 04061834059356 |
| M5005-500G | 04061834059363 |