M5883
7-Methylguanosine 5′-diphosphate sodium salt
≥92.5%, synthetic (organic), powder
别名:
7-Methyl-gdp, m7GDP
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关于此项目
经验公式（希尔记法）:
C11H17N5O11P2 · xNa+
化学文摘社编号:
分子量:
457.23 (free acid basis)
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥92.5%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
Storage temp.:
−20°C
产品名称
7-Methylguanosine 5′-diphosphate sodium salt, ≥92.5%
biological source
synthetic (organic)
Quality Level
assay
≥92.5%
form
powder
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
storage temp.
−20°C
SMILES string
[Na+].[Na+].C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13
InChI
1S/C11H17N5O11P2.2Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22;;/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChI key
VSMXIKIFPKDZJA-IDIVVRGQSA-L
General description
7-Methylguanosine 5′-diphosphate (m7GDP) is derived when the human decapping Dcp2 enzyme cleaves the cap of the deadenylated mRNAs during the 5′–3′ mRNA decay pathway.
Application
7-Methylguanosine 5′-diphosphate sodium salt has been used as a component of the elution buffer for the purification of 5’capped RNA.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M Długosz et al.
Journal of biochemical and biophysical methods, 51(2), 179-193 (2002-06-14)
A method for extracting kinetic and optical parameters from progress curves for protein-ligand association, obtained by stopped-flow experiments, is described. The method is limited to one-step and two-step association kinetics, but it allows concentration of protein and offset of the
Laurent Volpon et al.
RNA (New York, N.Y.), 23(6), 927-937 (2017-03-23)
The eukaryotic translation initiation factor eIF4E acts in the nuclear export and translation of a subset of mRNAs. Both of these functions contribute to its oncogenic potential. While the biochemical mechanisms that underlie translation are relatively well understood, the molecular
Magdalena Lewdorowicz et al.
RNA (New York, N.Y.), 10(9), 1469-1478 (2004-07-27)
Leishmania and other trypanosomatids are early eukaryotes that possess unusual molecular features, including polycistronic transcription and trans-splicing of pre-mRNAs. The spliced leader RNA (SL RNA) is joined to the 5' end of all mRNAs, thus donating a 5' cap that
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M5883-10MG | 04061833007778 |
| M5883-25MG | 04061833007785 |