M6751
5-甲基胞嘧啶 盐酸盐
≥99%, synthetic (organic), crystalline powder
别名:
4-氨基-2-羟基-5-甲基嘧啶
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关于此项目
经验公式（希尔记法）:
C5H7N3O · HCl
化学文摘社编号:
分子量:
161.59
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
261-223-9
MDL number:
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
crystalline powder
Solubility:
water: 50 mg/mL, clear to slightly hazy, colorless
产品名称
5-甲基胞嘧啶 盐酸盐, ≥99%
biological source
synthetic (organic)
Quality Level
assay
≥99%
form
crystalline powder
solubility
water: 50 mg/mL, clear to slightly hazy, colorless
SMILES string
O=C1NC(N)=C(C)C=N1.[H]Cl
InChI
1S/C5H7N3O.ClH/c1-3-2-7-5(9)8-4(3)6;/h2H,1H3,(H3,6,7,8,9);1H
InChI key
ANWMULVRPAUPJT-UHFFFAOYSA-N
Application
5-甲基胞嘧啶盐酸盐已被用作高效液相色谱（HPLC）法估计整体甲基化率的标准品。它还被用于高分辨率质谱分析。
5-甲基胞嘧啶被用于DNA甲基化过程（表观遗传学）的研究。
Biochem/physiol Actions
5-甲基胞嘧啶可介导基因表达、基因组印记和转位因子的抑制。它与翻译保真度和tRNA识别密切相关。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA
Squires JE, et al.
Nucleic Acids Research, 40(11), 5023-5033 (2012)
Absolute quantification of RNA or DNA using acid hydrolysis and mass spectrometry
Lowenthal MS, et al.
Analytical Chemistry, 6, 824-824 (2019)
Daniel Renciuk et al.
Nucleic acids research, 41(21), 9891-9900 (2013-08-22)
5-Hydroxymethylcytosine (5-hmC) was recently identified as a relatively frequent base in eukaryotic genomes. Its physiological function is still unclear, but it is supposed to serve as an intermediate in DNA de novo demethylation. Using X-ray diffraction, we solved five structures
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M6751-1G | 04061826739037 |
| M6751-250MG | 04061834061229 |