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Merck
CN

M7439

甲基-β-环糊精

别名:

Methyl-beta-cyclodextrin

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352201
NACRES:
NA.22
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form

powder

Quality Level

impurities

<10.0% water (Karl Fischer)

color

white

mp

180-182 °C (lit.)

SMILES string

O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

General description

甲基-β-环糊精是一种小的环七糖。

Application

甲基-β-环糊精已用作胆固醇螯合剂:
  • 研究其对小鼠心肌细胞的影响
  • 研究其对人角膜基质成纤维细胞的影响
  • 研究其对亲联蛋白-2 (JPH2)池的影响

Biochem/physiol Actions

甲基-β-环糊精参与增加细胞的渗透性。它还在细胞内的肌动蛋白骨架解聚中发挥作用。甲基-β-环糊精参与从血浆中吸引胆固醇。它参与激活某些细胞的细胞外受体激酶。

Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

368.6 °F

flash_point_c

187 °C

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rajiv R Mohan et al.
Experimental eye research, 180, 200-207 (2019-01-07)
Decorin (Dcn), a small leucine-rich proteoglycan, is involved in the regulation of corneal wound healing. Epidermal growth factor receptor (EGFR) plays a critical role in corneal fibroblasts proliferation, migration and extracellular matrix (ECM) modulation upon injury or infection. The present
Mario Menschikowski et al.
Cancer cell international, 11, 4-4 (2011-02-16)
Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried out
Sara Rodríguez-Acebes et al.
The Biochemical journal, 420(2), 305-315 (2009-03-06)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol



全球贸易项目编号

货号GTIN
M7439-1G04061834062042