M7898
单克隆抗 Thy 1.1 小鼠抗
clone TN-26, purified immunoglobulin, buffered aqueous solution
别名:
Anti-CD90, Anti-CDw90
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关于此项目
Conjugate:
unconjugated
Clone:
TN-26, monoclonal
Application:
IF, complement-mediated cytotoxicity assay
Citations:
18
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
TN-26, monoclonal
form
buffered aqueous solution
species reactivity
mouse
technique(s)
complement-mediated cytotoxicity assay: suitable, indirect immunofluorescence: suitable
isotype
IgM
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Thy1(21838)
General description
单克隆抗 Thy 1.1（小鼠 IgM 同种型）来源于小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生的杂交瘤。
胸腺细胞抗原 1 (Thy 1.1) 是一种糖基磷脂酰锚定蛋白。它属于免疫球蛋白超家族。Thy 1.1 在干细胞、T 细胞和神经元中表达。
Immunogen
AKR/J (Thy 1.1) 小鼠的胸腺细胞。
Application
小鼠源抗Thy 1.1单克隆抗体可用于免疫淘选和免疫荧光。
Biochem/physiol Actions
研究表明，缺乏蛋白质胸腺细胞抗原 1 (Thy 1.1) 的小鼠成纤维细胞数量增加。这种成分可抑制真皮成纤维细胞的增殖并增强其凋亡，从而调节细胞生长。此过程通过调节β3整合素的作用实现。
识别Thy 1.1轴承细胞，与Thy 1.2轴承细胞的交叉反应小于5%。根据对AKR / J胸腺细胞的体外细胞毒性测定，滴度为1:20,000
Physical form
0.1 M磷酸盐缓冲液（pH 7.4，含有15 mM叠氮化钠）溶液
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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wgk
nwg
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
J A Cohen et al.
Journal of neuroscience research, 31(4), 622-634 (1992-04-01)
The neu gene, which encodes a putative tyrosine kinase growth factor receptor termed p185neu, was originally identified as a dominant transforming gene in neurogliomas and schwannomas induced by transplacental treatment of rat embryos with ethylnitrosourea. The present studies were undertaken
Wendy A Neveu et al.
American journal of physiology. Cell physiology, 309(9), C616-C626 (2015-09-04)
Idiopathic pulmonary fibrosis is a progressive lung disease that increases in incidence with age. We identified a profibrotic lung phenotype in aging mice characterized by an increase in the number of fibroblasts lacking the expression of thymocyte differentiation antigen 1
Glial-mediated neuroprotection: Evidence for the protective role of the NO-cGMP pathway via neuron-glial communication in the peripheral nervous system.
Thippeswamy T, et al.
Glia, 49(2), 197-210 (2005)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M7898-.25ML | 04061834062455 |