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Merck
CN

M8639

2′-(4-甲基伞形酮)-α;-(4-甲基伞形酮)-α- D - N -乙酰神经氨酸 钠盐 水合物

fluorogenic, ≥95% (HPLC), powder

别名:

4-甲基伞形酮基- N -乙酰基-α- D -神经氨酸 钠盐 水合物

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关于此项目

经验公式(希尔记法):
C21H24NNaO11 · xH2O
化学文摘社编号:
分子量:
489.41 (anhydrous basis)
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
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产品名称

2′-(4-甲基伞形酮)-α;-(4-甲基伞形酮)-α- D - N -乙酰神经氨酸 钠盐 水合物, ≥95% (HPLC)

Quality Level

assay

≥95% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to light yellow

storage temp.

−20°C

SMILES string

O.[H]C(O)(CO)[C@]([H])(O)[C@@H]1OC(C[C@H](O)[C@H]1NC(C)=O)(Oc2ccc3C(C)=CC(=O)Oc3c2)C(=O)O[Na]

InChI

1S/C21H25NO11.Na.H2O/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);;1H2/q;+1;/p-1/t13-,14?,17+,18?,19+,21+;;/m0../s1

InChI key

NSQMRVBWXQQIKF-NVRWCLOTSA-M

Biochem/physiol Actions

神经氨酸酶荧光测定法的底物。用于 PAGE 中唾液酸酶的荧光染色。



存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.


Li Zhang et al.
Viruses, 12(5) (2020-05-24)
Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and mortality and posing a great threat to human health. Because of the diversity of influenza virus strains and drug resistance
Guo-Yun Chen et al.
eLife, 3, e04066-e04066 (2014-09-05)
Both pathogen- and tissue damage-associated molecular patterns induce inflammation through toll-like receptors (TLRs), while sialic acid-binding immunoglobulin superfamily lectin receptors (Siglecs) provide negative regulation. Here we report extensive and direct interactions between these pattern recognition receptors. The promiscuous TLR binders
Ge Liu et al.
Virologica Sinica, 34(6), 648-661 (2019-07-10)
Severe influenza infections are often associated with the excessive induction of pro-inflammatory cytokines, which is also referred to as "cytokine storms". Several studies have shown that cytokine storms are directly associated with influenza-induced fatal acute lung injury and acute respiratory



全球贸易项目编号

货号GTIN
M8639-5MG04061834063414
M8639-1MG04061834063391
M8639-25MG04061834063407