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Merck
CN

MAK055

天冬氨酸转氨酶(AST)活性检测试剂盒

sufficient for 100 colorimetric tests

别名:

SGOT活性检测试剂盒, 天冬氨酸转氨酶活性检测试剂盒, 血清谷氨酸-草酰乙酸转氨酶活性检测试剂盒, 谷氨酸-草酰乙酸转氨酶活性检测试剂盒

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关于此项目

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 colorimetric tests

species reactivity

rat, human, human, rat, mouse, mouse

packaging

pkg of 1 ea

storage condition

dry at room temperature

technique(s)

activity assay: suitable

input

liquid

accession no.

P17174, NM_002079.3, NM_010324.2

UniProt accession no.

detection method

colorimetric

relevant disease(s)

gastrointestinal diseases; cardiovascular diseases

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GOT1(2805)
mouse ... GOT1(14718)
rat ... GOT1(24401)

General description

现在我们可提供全新的天冬氨酸转氨酶检测试剂盒MAK467!天冬氨酸转氨酶(AST),以前被称为血清谷草转氨酶(SGOT),是一种吡哆醛磷酸盐(PLP)依赖酶,催化天冬氨酸和α-酮戊二酸转化成草酰乙酸和谷氨酸。和丙氨酸转氨酶(ALT)类似,血液中AST水平通常作为肝功能标记物。但是,AST分布的器官范围比ALT要广,AST水平的变化可能是疾病或多性器官损伤引起,包括骨骼和心脏。

Application

AST活性分析试剂盒可以用来检测样本中天冬氨酸转氨酶活性。
适用于测量组织、细胞和血清等各种生物样品中的天冬氨酸转氨酶(AST)活性。

Biochem/physiol Actions

天冬氨酸转氨酶活性分析试剂盒提供简单和直接的方法,用于检测各种样本中的AST活性。在该试剂盒中,天冬氨酸上的氨基基团转移到α酮戊二酸上,生成谷氨酸,生成的比色(450nm)产物和AST酶活性成正比。一单位的AST是37℃,pH8.0,生成 1.0 μmole的谷氨酸的酶当量。

Features and Benefits

兼容高通量处理系统。


pictograms

Health hazardCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

法规信息

低风险生物材料

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历史批次信息供参考:

分析证书(COA)

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Leola N Chow et al.
PloS one, 11(3), e0151765-e0151765 (2016-03-22)
Modulation of chemokine CXCL12 and its receptor CXCR4 has been implicated in attenuation of bleomycin (BLM)-induced pulmonary fibrosis and carbon tetrachloride (CCl4)-induced hepatic injury. In pulmonary fibrosis, published reports suggest that collagen production in the injured lung is derived from
Resolvin D1 and E1 alleviate the progress of hepatitis toward liver cancer in long-term concanavalin A-induced mice through inhibition of NF-KB activity.
Kuang H, et al.
Oncology Reports, 35, 307-317 (2016)
Xinyi Xu et al.
Microbiology (Reading, England), 161(6), 1219-1230 (2015-03-27)
Aspartate and glutamate are two key amino acids used in biosynthesis of many amino acids that play vital role in cellular metabolism. Aspartate aminotransferases (AspATs) are required for channelling nitrogen (N(2)) between Glu and Asp in all life forms. Biochemical



全球贸易项目编号

货号GTIN
MAK055-1KT04061834064992