usage
sufficient for 200 fluorometric tests (red)
detection method
fluorometric
relevant disease(s)
neurological disorders; cancer
storage temp.
−20°C
General description
活性氧 (ROS) 是由于有氧呼吸过程中氧气减少和细胞内各种酶系统产生的。在生理水平,活性氧有助于细胞信号和宿主防御。ROS 生成增加,高于生物系统的解毒能力,导致氧化应激和细胞损伤。对细胞的主要损伤是由 ROS 诱导的膜脂、必需蛋白质和 DNA 中的多不饱和脂肪酸等大分子的改变所致。ROS 与阿尔茨海默病、帕金森病、癌症、衰老等疾病状态有关。
Application
荧光细胞内活性氧 (ROS) 试剂盒已用于检测活细胞中的细胞内 ROS。
本试剂盒适于通过酶标仪或荧光显微镜检测细胞内的ROS。
Biochem/physiol Actions
试剂盒提供灵敏的一步荧光测定方法,不用孵育1小时即可检测活细胞的胞内 ROS(特别是超氧化物和羟基自由基)。ROS与细胞透过性传感器反应,生成的荧光产物(λex = 520/λem = 605 nm)与 ROS 量成比例。这一测定可用荧光微板读取仪,在96孔或384孔多孔板中进行。
Still not finding the right product?
Explore all of our products under 细胞内ROS检测试剂盒(红色荧光)
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Knockdown of ferroportin accelerates erastin-induced ferroptosis in neuroblastoma cells.
Geng N, et al.
European Review for Medical and Pharmacological Sciences, 22(12), 3826-3836 (2018)
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer.
Matassa D S, et al.
Cell Death and Differentiation, 23(9), 1542-1542 (2016)
Reactive oxygen species (ROS) and response of antioxidants as ROS-scavengers during environmental stress in plants.
Das K and Roychoudhury A
Frontiers in Endocrinology, 2, 53-53 (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAK145-1KT | 04061834407027 |