recombinant
expressed in CHO cells
Quality Level
antibody product type
primary antibodies
form
lyophilized powder
shipped in
wet ice
storage temp.
−20°C
General description
SigmaMab抗体药物偶联物(ADC)模拟物是一种可用作质谱和高效液相色谱标准品的无毒性药物模拟物。ADC模拟物可通过LC-SMCC交联剂将SigmaMab(MSQC4)这种IgG1单克隆抗体与丹磺酰荧光团进行偶联。这种丹酰-LC-SMCC附着物可取代真实ADC的有毒载荷。
ADC模拟物可实现更安全、更一致的测试,使其成为优于真实ADC的最佳产品。与真实的ADC相比,它也是一种更具实惠的产品。借助这种无毒产品,LC-MS工艺可在更为安全的环境中被开发。
ADC模拟物可实现更安全、更一致的测试,使其成为优于真实ADC的最佳产品。与真实的ADC相比,它也是一种更具实惠的产品。借助这种无毒产品,LC-MS工艺可在更为安全的环境中被开发。
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存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
常规特殊物品
此项目有
实验方案
SigmaMab Antibody Drug Conjugate Mimic, is a non-toxic drug mimic utilized as a standard for mass spectrometry and high performance liquid chromatography.
Here we show how LC and MS methods may be optimized using a non-toxic surrogate of the ADC, an “ADC-mimic”, that behaves very similarly to the Cys-linked ADC Adcetris (Seattle Genetics).
商品
Intact analysis of Universal Antibody Standard human and Antibody-Drug Conjugate (ADC) Mimic on silica monolithic HPLC columns under various conditions.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MSQC8-0.5MG | 04061833254820 |