跳转至内容
Merck
CN

主要文件

查看所有文档

N0258

N-亚硝基二乙胺

ISOPAC®

别名:

二乙基亚硝胺

登录 查看组织和合同定价。

选择尺寸

变更视图

关于此项目

线性分子式:
(C2H5)2NNO
化学文摘社编号:
55-18-5
分子量:
102.14
UNSPSC Code:
12352116
NACRES:
NA.25
PubChem Substance ID:
24897417
EC Number:
200-226-1
Beilstein/REAXYS Number:
1744991
MDL number:
MFCD00013890
Form:
liquid
Quality level:
100
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

Quality Level

100

form

liquid

bp

177 °C (lit.)

density

0.95 g/mL (lit.)

SMILES string

CCN(CC)N=O

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI key

WBNQDOYYEUMPFS-UHFFFAOYSA-N

Application

N-亚硝基二乙胺（NDEA）已被用作肝致癌物/DNA损伤剂。它已被用作气液色谱的校准标准品。

Biochem/physiol Actions

N-亚硝基二乙胺（NDEA）是一种有效的肝癌性二烷基亚硝胺。它主要存在于烟草烟雾、水、切达干酪、腌制油炸食品和许多酒精饮料中。NDEA与DNA修复/复制相关的核酶的变化相关。它会导致所有动物物种中的多种肿瘤。其主要靶器官是鼻腔、气管、肺、食道和肝脏。

Packaging

包装于100mL带有硅/PTFE胶垫和铝质撕裂密封的血清瓶中。

Preparation Note

将内容物溶解在100mL溶剂中，可得到1％的溶液。

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

通过注入任何相容的溶剂可在不暴露内容物的情况下制备任何所需强度的溶液。

Still not finding the right product?

Explore all of our products under N-亚硝基二乙胺

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCN8521
MKCM0585
MKCK9777
MKCK9778
MKCJ7568

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

商品

DNA损伤和修复

DNA损伤和修复机制对于维持DNA完整性至关重要。细胞DNA的损伤与突变、癌症发展等有关。

DNA Damage and Repair

DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Chemopreventive effect of hydroethanolic extract of Euphorbia neriifolia leaves against DENA-induced renal carcinogenesis in mice.
Pracheta P
Asian Pacific Journal of Cancer Prevention, 12, 677-677 (2011)
Yewei Liu et al.
International journal of cancer, 143(7), 1817-1828 (2018-05-01)
To better inform the next clinical trials of vascular disrupting agent combretastatin-A4-phosphate (CA4P) in patients with hepatic malignancies, this preclinical study aimed at evaluating CA4P therapeutic efficacy in rats with primary hepatocellular carcinomas (HCCs) of a full spectrum of differentiation
Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark.
Singh BN
Chemico-Biological Interactions, 181, 20-20 (2009)
查看所有相关文献

全球贸易项目编号

货号GTIN
N0258-1G04061834092803