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Merck
CN

N4779

5-硝基-2-(3-苯基丙基氨基)苯甲酸

≥98%, chloride channel blocker, solid

别名:

NPPB

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关于此项目

经验公式(希尔记法):
C16H16N2O4
化学文摘社编号:
分子量:
300.31
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98%
Form:
solid
Quality level:
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产品名称

5-硝基-2-(3-苯基丙基氨基)苯甲酸, ≥98%

Quality Level

assay

≥98%

form

solid

solubility

ethanol: 3 mg/mL, DMSO: 37 mg/mL, H2O: insoluble

storage temp.

−20°C

SMILES string

OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O

InChI

1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)

InChI key

WBSMIPAMAXNXFS-UHFFFAOYSA-N

Biochem/physiol Actions

强效氯离子通道阻滞剂。

Features and Benefits

该化合物在受体分类和信号转导手册的氯化物通道页面上有重点介绍。想要浏览手册的其他页面, 请单击此处


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anaïs Merckx et al.
PLoS pathogens, 4(2), e19-e19 (2008-02-06)
Malaria symptoms occur during Plasmodium falciparum development into red blood cells. During this process, the parasites make substantial modifications to the host cell in order to facilitate nutrient uptake and aid in parasite metabolism. One significant alteration that is required
Tae Sik Sung et al.
The Journal of physiology, 596(9), 1549-1574 (2018-02-13)
Enteric neurotransmission is essential for gastrointestinal (GI) motility, although the cells and conductances responsible for post-junctional responses are controversial. The calcium-activated chloride conductance (CaCC), anoctamin-1 (Ano1), was expressed by intramuscular interstitial cells of Cajal (ICC-IM) in proximal stomach and not
Michael R Bristow et al.
JACC. Basic to translational science, 5(9), 871-883 (2020-08-25)
Using serial analysis of myocardial gene expression employing endomyocardial biopsy starting material in a dilated cardiomyopathy cohort, we show that mRNA expression of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) cardiac myocyte receptor ACE2 is up-regulated with remodeling and with reverse



全球贸易项目编号

货号GTIN
N4779-100MG04061832575087
N4779-25MG04061834116738