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Merck
CN

N6250

1,3-二羟基萘

≥99% purity , crystalline

别名:

1,3-萘二酚, 间萘二酚

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关于此项目

线性分子式:
C10H6(OH)2
化学文摘社编号:
分子量:
160.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
205-079-7
MDL number:
Beilstein/REAXYS Number:
2044002
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产品名称

1,3-二羟基萘, ≥99%, crystalline

Quality Level

assay

≥99%

form

crystalline

technique(s)

titration: suitable

color

white to tan

mp

123-125 °C (lit.), 124-125 °C

solubility

ethanol: 50 mg/mL

λmax

288 nm (298 nm (ethanol))

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1cc(O)c2ccccc2c1

InChI

1S/C10H8O2/c11-8-5-7-3-1-2-4-9(7)10(12)6-8/h1-6,11-12H

InChI key

XOOMNEFVDUTJPP-UHFFFAOYSA-N

General description

1,3-二羟基萘是一种染料中间体,当其结合特定的媒染剂和混合其他氧化染料时,可形成稳定的颜色物质。该试剂专用于比色定量测定糖醛酸,如来自尿液的葡萄糖醛酸。已有研究显示1,3-二羟基萘的臭氧化衍生物对数种鼠伤寒沙门氏杆菌菌株具有致突变性。

Application

1,3-二羟基萘可用于糖类色谱分析,有时可与间苯二酚联用。已应用于薄层电泳法,用于分析含有单、寡和多糖和衍生物以及酚类物质的生物质降解产物。

Preparation Note

1,3-二羟基萘可溶于乙醇(50 mg/ml)(必要时可加热),产生澄清至微浊、无色至橘棕色溶液。也可溶于水和醚。


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Muta. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Y Sayato et al.
Mutation research, 189(3), 217-222 (1987-11-01)
The mutagenicity of products formed by ozonation of naphthoresorcinol in aqueous solution was assayed with Salmonella typhimurium strains TA97, TA98, TA100, TA102 and TA104 in the presence and absence of S9 mix from phenobarbital- and 5,6-benzoflavone-induced rat liver. Ozonated naphthoresorcinol
Karen A Nolan et al.
Bioorganic & medicinal chemistry letters, 20(24), 7331-7336 (2010-11-16)
The NCI chemical database has been screened using in silico docking to identify novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Compounds identified from the screen exhibit a diverse range of scaffolds and inhibitory potencies are generally in the micromolar range.
Wilson Terán et al.
The Journal of biological chemistry, 281(11), 7102-7109 (2006-01-13)
The RND family transporter TtgABC and its cognate repressor TtgR from Pseudomonas putida DOT-T1E were both shown to possess multidrug recognition properties. Structurally unrelated molecules such as chloramphenicol, butyl paraben, 1,3-dihydroxynaphthalene, and several flavonoids are substrates of TtgABC and activate



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货号GTIN
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