N7634
硝苯地平
≥98% (HPLC), powder, L-type Ca²⁺ channel blocker
别名:
1,4-二氢-2,6-二甲基-4-(2-硝基苯基)-3,5-吡啶二甲酸二甲酯
选择尺寸
关于此项目
产品名称
硝苯地平, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
yellow
solubility
DMSO: soluble, ethanol: soluble
originator
Bayer
storage temp.
2-8°C
SMILES string
COC(=O)C1=C(C)NC(C)=C(C1c2ccccc2[N+]([O-])=O)C(=O)OC
InChI
1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChI key
HYIMSNHJOBLJNT-UHFFFAOYSA-N
Gene Information
human ... ADORA2A(135), ADORA3(140), CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNA2D1(781), CYP1A2(1544), KCNH1(3756), TTR(7276)
mouse ... Cacna1c(12288)
rat ... Adora1(29290), Adora2a(25369), Cacna1c(24239), Cacna1d(29716), Kcnj1(24521), Kcnn4(65206), Tbxas1(24886)
Application
- 评估其对豚鼠小肠R-型钙通道中肌间神经元钙电流的影响
- 评估L型钙通道阻滞剂对胆碱能和多巴胺能神经元的神经保护作用
- 确定硝苯地平（抗高血压药物）与降糖药共同给药对人脐静脉细胞（HUVEC）的影响
Biochem/physiol Actions
Features and Benefits
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
Discover Bioactive Small Molecules for ADME/Tox
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| N7634-10G | 04061834118121 |
| N7634-25G | 04061834118138 |
| N7634-1G | 04061835516186 |
| N7634-5G | 04061834118145 |