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N7778

7-硝基吲唑

≥98%

别名:

7-NI

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关于此项目

经验公式（希尔记法）:
C7H5N3O2
化学文摘社编号:
2942-42-9
分子量:
163.13
NACRES:
NA.77
PubChem Substance ID:
24278047
UNSPSC Code:
12352200
EC Number:
220-934-4
MDL number:
MFCD00022789
Assay:
≥98%
Form:
powder
Quality level:
100
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Quality Level

100

assay

≥98%

form

powder

solubility

DMF: 50 mg/mL, clear, yellow to orange

storage temp.

−20°C

SMILES string

[O-][N+](=O)c1cccc2cn[nH]c12

InChI

1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)

InChI key

PQCAUHUKTBHUSA-UHFFFAOYSA-N

Gene Information

human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
rat ... Nos1(24598)

Biochem/physiol Actions

小鼠大脑一氧化氮合酶的选择性抑制剂。

Features and Benefits

该化合物在受体分类和信号转导手册的一氧化氮合酶页面上有重点介绍。想要浏览手册的其他页面， 请单击此处。

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCJ7802
MKCD7162
MKBS6671V
MKBQ5158V
SLBG0212V

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J Garthwaite
Trends in neurosciences, 14(2), 60-67 (1991-02-01)
Nitric oxide (NO) is a recently discovered and highly unorthodox messenger molecule. Current evidence indicates that, in the CNS, NO is produced enzymatically in postsynaptic structures in response to activation of excitatory amino acid receptors. It then diffuses out to
Morten Hedetoft et al.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 45(3), 335-350 (2018-07-22)
Experiments have shown that hyperbaric oxygen (HBO2) therapy reduces cyanide-induced cerebral distress. The exact mechanism behind HBO2's neuroprotective effect is unknown, but has been proposed to be mediated by an increased neuronal nitric oxide (NO) bioavailability, which may compete with
Anita J Turner et al.
American journal of physiology. Renal physiology, 313(4), F864-F873 (2017-07-07)
Via developmental programming, prenatal perturbations, such as exposure to glucocorticoids and maternal malnutrition alter kidney development and contribute to the development of hypertension. To examine the possibility that alterations in tubuloglomerular feedback (TGF) contribute to the development of hypertension in
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全球贸易项目编号

货号GTIN
N7778-1G04061834118213
N7778-5G04061834118220