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N8160

β-烟酰胺腺嘌呤二核苷酸磷酸 钠盐

pkg of 10 mg (per vial)

别名:

β-NADP-钠, β-NADP-钠盐, NADP, TPN, TPN-Na, 三磷酸吡啶核苷酸 钠盐, 辅酶II 钠盐

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关于此项目

线性分子式:
C21H27N7O17P3 · Na
化学文摘社编号:
1184-16-3
分子量:
765.39
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
24897856
EC Number:
214-664-6
Beilstein/REAXYS Number:
4779954
MDL number:
MFCD00036973
Form:
powder
Solubility:
water: 0.05 g/L
Storage temp.:
−20°C
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form

powder

Quality Level

200

packaging

pkg of 10 mg (per vial)

mp

175-178 °C (dec.) (lit.)

solubility

water: 0.05 g/L

storage temp.

−20°C

SMILES string

[Na+].[H]O[H].NC(=O)c1ccc[n+](c1)C2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@@H]([C@@H]3O)P(O)(O)=O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H28N7O16P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(45(33,34)35)14(30)11(43-21)6-41-47(38,39)44-46(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1

InChI key

NLIGHACCLYZCOM-FHQWUTKFSA-M

Application

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biochem/physiol Actions

电子受体

Other Notes

根据UV-Vis确定的NADP含量进行包装。
这是NADP的常见形式。不要与3'-NADP或α-NADP混淆。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCD2321
SLBV4637
SLBT7105
SLBS1589V
SLBM1252V

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Rong Zhang et al.
American journal of respiratory and critical care medicine, 192(3), 315-323 (2015-05-07)
Lung-protective ventilatory strategies have been widely used in patients with acute respiratory distress syndrome (ARDS), but the ARDS mortality rate remains unacceptably high and there is no proven pharmacologic therapy. Mechanical ventilation can induce oxidative stress and lung fibrosis, which
Haiqin Chen et al.
Scientific reports, 5, 11247-11247 (2015-06-11)
Microorganisms are valuable resources for lipid production. What makes one microbe but not the other able to efficiently synthesize and accumulate lipids is poorly understood. In the present study, global gene expression prior to and after the onset of lipogenesis
Bevan P Gang et al.
Cancer biology & therapy, 15(11), 1533-1541 (2014-12-09)
Deregulated metabolism is gaining recognition as a hallmark of cancer cells, and is being explored for therapeutic potential. The Warburg effect is a metabolic phenotype that occurs in 90% of tumors, where glycolysis is favored despite the presence of oxygen.
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全球贸易项目编号

货号GTIN
N8160-15VL04061834118435
N8160-1VL04061837151583