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关于此项目
经验公式(希尔记法):
C11H19IN2O
化学文摘社编号:
分子量:
322.19
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
solid
Quality level:
产品名称
氧化震颤素M, solid
form
solid
Quality Level
color
white
solubility
H2O: 24 mg/mL, ethanol: 4.6 mg/mL
storage temp.
2-8°C
SMILES string
[I-].C[N+](C)(C)CC#CCN1CCCC1=O
InChI
1S/C11H19N2O.HI/c1-13(2,3)10-5-4-8-12-9-6-7-11(12)14;/h6-10H2,1-3H3;1H/q+1;/p-1
InChI key
VVLMSCJCXMBGDI-UHFFFAOYSA-M
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
Application
氧化震颤素M已用作毒蕈碱型乙酰胆碱受体(mAchR)激动剂:
- 用于研究其对秀丽隐杆线虫移动的急性效应
- 用于处理海马体神经元,以便研究成纤维细胞生长因子受体1(FGFR1)的磷酸化作用
- 用于诱发大鼠膀胱过度活动症
Biochem/physiol Actions
氧化震颤素M是一种非选择性毒蕈碱型乙酰胆碱受体激动剂。
Features and Benefits
这种化合物是神经科学研究的特色产品。点击此处发现更多特色神经科学产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Wiebke K Seemann et al.
The Journal of pharmacology and experimental therapeutics, 360(2), 289-299 (2017-01-14)
Drug discovery strives for selective ligands to achieve targeted modulation of tissue function. Here we introduce engineered context-sensitive agonism as a postreceptor mechanism for tissue-selective drug action through a G protein-coupled receptor. Acetylcholine M
Simona Dedoni et al.
Journal of neurochemistry, 122(1), 58-71 (2012-04-27)
Type I interferons (IFNs) have been shown to act on neurons and to cause neuronal damage through mechanisms not completely defined. Here, we investigated the effects of type I IFNs on brain-derived neurotrophic factor (BDNF)-induced TrkB receptor signaling and neurotrophic
Paola Correa et al.
PLoS genetics, 8(11), e1003015-e1003015 (2012-11-21)
Caenorhabditis elegans male copulation requires coordinated temporal-spatial execution of different motor outputs. During mating, a cloacal circuit consisting of cholinergic sensory-motor neurons and sex muscles maintains the male's position and executes copulatory spicule thrusts at his mate's vulva. However, distinct
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| O100-100MG | 04061834212690 |
| O100-500MG | 04061838065063 |
