O6881
奥昔嘌醇
≥98% (HPLC)
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关于此项目
经验公式（希尔记法）:
C5H4N4O2
化学文摘社编号:
分子量:
152.11
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
219-570-9
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Solubility:
1 M NaOH: 49.00-51.00 mg/mL, clear to slightly hazy, colorless to yellow (heated NaOH)
Quality Level
assay
≥98% (HPLC)
form
powder
solubility
1 M NaOH: 49.00-51.00 mg/mL, clear to slightly hazy, colorless to yellow (heated NaOH)
SMILES string
O=C1NC(=O)c2cn[nH]c2N1
InChI
1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)
InChI key
HXNFUBHNUDHIGC-UHFFFAOYSA-N
Application
氧嘌呤醇已被用作黄嘌呤氧化酶抑制剂，以评估其对肝癌细胞增殖的影响。它也已被用作黄嘌呤抑制剂，以阐明其在诱导hpv16晚期基因表达中的作用。
氧嘌呤醇是一种别嘌呤醇代谢产物，被用作抑制剂来研究黄嘌呤氧化酶的特异性和动力学。氧嘌呤醇还通过抑制黄嘌呤氧化酶而用作抗炎药。
Biochem/physiol Actions
氧嘌呤醇具有刺激成骨细胞分化和增强骨形成的能力。用于治疗痛风和高尿酸血症。氧嘌呤醇被认为是一种强抗氧化剂。它能阻止成骨细胞黄嘌呤氧化酶（XO）的作用。
一种别嘌醇的代谢产物。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Jan B Derks et al.
Pediatric research, 68(5), 374-380 (2010-07-09)
In complicated labor, neonatal outcome may depend not only on the extent of fetal asphyxia and acidosis but also on the effects on the fetal cardiovascular system of reactive oxygen species (ROS) generated during the ischemia-reperfusion (I/R) associated with repeated
L K Stamp et al.
Clinical pharmacology and therapeutics, 90(3), 392-398 (2011-07-29)
The treatment of gout requires a lowering of serum urate (SU) levels, and allopurinol is the drug that is most commonly used for this purpose. The objectives of this study were to define the relationships between allopurinol dose on the
Adenosine causes read-through into the late region of the HPV16 genome in a guanosine-dependent manner
Yu H, et al.
Virology, 521(9), 1-19 (2018)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| O6881-500MG | 04061833612446 |
| O6881-100MG | 04061834248347 |