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Merck
CN

P0233

Anti-Potassium Channel Kv4.2 (Shal1; RK5; Kcnd2) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB CL
Citations:
3
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, human

technique(s)

western blot (chemiluminescent): 1:200-1:300

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCND2(3751)
rat ... Kcnd2(65180)

Immunogen

synthetic peptide corresponding to amino acids 454-469 of rat potassium channel Kv4.2 (with additional N-terminal cysteine). The epitope is identical in human and highly homologous in mouse.

Application

western blot (chemiluminescent): 1:200-1:300

Biochem/physiol Actions

Recognizes full-length Kv4.2 protein.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料
常规特殊物品
含少量动物源组分生物产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alicia M Hall et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(15), 6221-6230 (2015-04-17)
Neuronal hyperexcitability occurs early in the pathogenesis of Alzheimer's disease (AD) and contributes to network dysfunction in AD patients. In other disorders with neuronal hyperexcitability, dysfunction in the dendrites often contributes, but dendritic excitability has not been directly examined in
S L Roberds et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(5), 1798-1802 (1991-03-01)
Five distinct K+ channel cDNA molecules (RK1 to RK5) were cloned from either rat heart or rat aorta cDNA libraries. Four of the channels, RK1 to RK4, are similar or identical to Shaker-like K+ channels previously identified in rat brain
T J Baldwin et al.
Neuron, 7(3), 471-483 (1991-09-01)
A cDNA clone encoding a K+ channel polypeptide with 72% amino acid sequence identity to Drosophila Shal was isolated from rat hippocampus. Functional expression of the cDNA in Xenopus oocytes generated 4-amino-pyridine-sensitive K+ channels displaying rapid inactivation kinetics. The fastest



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货号GTIN
P0233-.2ML04061837813429