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关于此项目
线性分子式:
(HO)2P(O)OCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
185.07
NACRES:
NA.32
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
206-986-0
MDL number:
Beilstein/REAXYS Number:
1726826
产品名称
O-磷酸-L-丝氨酸,
form
powder
Quality Level
storage condition
under inert gas
mp
190 °C (lit.)
SMILES string
N[C@@H](COP(O)(O)=O)C(O)=O
InChI
1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
InChI key
BZQFBWGGLXLEPQ-REOHCLBHSA-N
Gene Information
human ... GRM4(2914), GRM7(2917), GRM8(2918)
Application
O -磷酸- L -丝氨酸已被用于:
- 蛋白的表达、纯化和磷酸化
- 研究其化学位移
- 采用拉曼光谱光谱法测定其 pKa 值
Biochem/physiol Actions
O-磷酸-L-丝氨酸 (O-Phospho-L-serine,L-SOP) 是一种类似磷脂酰丝氨酸头部基团的分子,它介导小胶质细胞吞噬凋亡细胞的部分抑制作用。在斑马鱼中,L-SOP 抑制 Müller 神经胶质细胞增殖并阻断光损伤视网膜中的视锥细胞再生。 在体内 ,L-SOP 作为 CysM 的底物,CysM 是来自 结核分枝杆菌的半胱氨酸合成酶 。
III 组亲代谢型谷氨酸受体激动剂(mGluR4、mGluR7 和 mGluR8)。
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Explore all of our products under O-磷酸-L-丝氨酸
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Improved peak identification in 31P-NMR spectra of environmental samples with a standardized method and peak library
Cade-Menun BJ
Geoderma, 257, 102-114 (2015)
The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Muller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina.
Bailey TJ
Experimental Eye Research, 91(5), 601-612 (2010)
Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
Richter B, et al.
Proceedings of the National Academy of Sciences of the USA, 113(15), 4039-4044 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P0878-1G | 04061834353157 |
| P0878-10MG | 04061833007907 |
| P0878-25G | 04061833007914 |
| P0878-5G | 04061833007921 |
