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Merck
CN

P1034

异硫氰酸苯酯

Sigma Grade, 8.36 M, suitable for solid phase protein sequencing analysis, ≥99% (GC), liquid

别名:

PITC

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关于此项目

线性分子式:
C6H5NCS
化学文摘社编号:
分子量:
135.19
UNSPSC Code:
12352118
NACRES:
NA.31
PubChem Substance ID:
EC Number:
203-138-1
Beilstein/REAXYS Number:
471392
MDL number:
Assay:
≥99% (GC)
Form:
liquid
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grade

Sigma Grade

assay

≥99% (GC)

form

liquid

concentration

8.36 M

refractive index

n20/D 1.6515 (lit.)

bp

218 °C (lit.)

mp

−21 °C (lit.)

density

1.132 g/mL at 20 °C (lit.)

suitability

suitable for solid phase protein sequencing analysis

storage temp.

2-8°C

SMILES string

S=C=Nc1ccccc1

InChI

1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H

InChI key

QKFJKGMPGYROCL-UHFFFAOYSA-N

General description

异硫氰酸苯酯属于带异硫氰酸基团的芳香族化合物类。它通常用作柱前衍生剂,用于形成苯硫代氨基甲酰基氨基酸,以便通过色谱技术进行测定。

Application

异硫氰酸苯酯可用于通过自动埃德曼反应和之后的高效液相色谱分析(HPLC)技术,在亚皮摩尔和亚纳摩尔水平进行多肽和蛋白质测序。
用于伯胺和仲胺的衍生化试剂。用于通过 Edman 降解法进行多肽测序以及通过 HPLC 进行氨基酸分析。

Packaging

氩气下用火焰封装的 1mL 棕色安瓿瓶包装。
氩气下装瓶的 10mL 螺纹盖棕色样品瓶包装。


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

190.4 °F - closed cup

flash_point_c

88 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R F Ebert
Analytical biochemistry, 154(2), 431-435 (1986-05-01)
A method for analysis of phenylthiocarbamyl-amino acids by HPLC is described. Solvent A contains 0.05 M sodium acetate plus triethylamine (2.75 ml/liter) adjusted to pH 6.40 with phosphoric acid. Solvent B consists of 50% solvent A, 40% acetonitrile, and 10%
R L Heinrikson et al.
Analytical biochemistry, 136(1), 65-74 (1984-01-01)
Methods for the quantitative derivatization of amino acids with phenylisothiocyanate and for the separation and quantitation of the resulting phenylthiocarbamyl derivatives by reverse-phase high-performance liquid chromatography are described. Phenylthiocarbamylation of amino acids proceeds smoothly in 5 to 10 min at
Examination of automated polypeptide sequencing using standard phenyl isothiocyanate reagent and subpicomole high-performance liquid chromatographic analysis
Tempst P and Riviere L
Analytical Biochemistry, 183(2), 290-300 (1989)



全球贸易项目编号

货号GTIN
P1034-10ML04061834353867
P1034-10X1ML04061834353874
P1034-1ML04061838174888