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P1793

匹莫齐特

Name: 匹莫齐特
Brand: SIGMA

≥98% (TLC), powder, D₂ dopamine receptor antagonist

别名:

1-[1-[4,4-双（4-氟苯基）丁基]-4-哌啶基]-1,3-二氢-2H-苯并咪唑-2-酮

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关于此项目

经验公式（希尔记法）:

C₂₈H₂₉F₂N₃O

化学文摘社编号:

2062-78-4

分子量:

461.55

NACRES:

NA.77

PubChem Substance ID:

24277923

UNSPSC Code:

12352200

EC Number:

218-171-7

MDL number:

MFCD00055081

Form:

powder

Quality level:

200

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属性

产品名称

匹莫齐特,

form

powder

Quality Level

200

solubility

DMSO: 18 mg/mL(lit.), chloroform: 5 mg/mL, H₂O: insoluble(lit.)

originator

Teva

storage temp.

2-8°C

SMILES string

Fc1ccc(cc1)C(CCCN2CCC(CC2)N3C(=O)Nc4ccccc34)c5ccc(F)cc5

InChI

1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)

InChI key

YVUQSNJEYSNKRX-UHFFFAOYSA-N

Gene Information

human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Scnn1g(24768)

说明

Biochem/physiol Actions

D ₂ 多巴胺受体拮抗剂；与克隆的 5-HT ₇ 受体高亲和力结合；Ca ^{2 +} 通道拮抗剂；抗精神病药

Features and Benefits

该化合物在受体分类和信号转导手册的环核苷酸门控（CNG）和超极化激活的环核苷酸门控（HCN）通道页面上有详细描述。想要浏览手册的其他页面，请单击此处。

该化合物是环核苷酸研究的特色产品。点击此处，发现更多特色环核苷酸产品。。在 sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子。

该化合物由 Teva 开发。如需浏览其他制药公司开发的化合物和批准的药物/候选药物列表，请点击此处。

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pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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