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Merck
CN

P1941

聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide (75:25), mol wt 66,000-107,000

别名:

LACTEL® B6007-1, PLGA

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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form

pellets

Quality Level

feed ratio

lactide:glycolide (75:25)

mol wt

66,000-107,000

storage temp.

−20°C

SMILES string

OCC(O)=O.CC(O)C(O)=O

InChI key

XBBVURRQGJPTHH-UHFFFAOYSA-N

General description

本品是一种无定形固体,转变温度(Tg)范围为45-50℃。它可溶于大多数有机溶剂,如二氯甲烷、四氢呋喃、乙酸乙酯、丙酮、氯仿和六氟异丙醇。

Application

聚(D,L-丙交酯-CO-乙交酯)是一种合成氨基酸,已可用于递送大分子治疗药物。

Features and Benefits

控释生物活性剂、缝线和可生物吸收植入器件。

Physical form

具有生物相容性且可生物降解的聚合物。

Legal Information

Lactel is a registered trademark of Evonik Corp


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.


Fabrication of amorphous strontium polyphosphate microparticles that induce mineralization of bone cells in vitro and in vivo
Werner E.G.Muller
Acta Biomaterialia, 50, 89-101 (2017)
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or



全球贸易项目编号

货号GTIN
P1941-1G04061834357322
P1941-5G04061834357346