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Merck
CN

P3644

L-α-磷脂酰胆碱

from soybean, Type IV-S, ≥30% (enzymatic)

别名:

1,2-二酰基-sn-甘油-3-胆碱磷酸, 3-sn-磷脂酰胆碱, L-α-卵磷脂, Azolectin, PC

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关于此项目

化学文摘社编号:
UNSPSC Code:
51321705
NACRES:
NA.25
EC Number:
232-307-2
Beilstein/REAXYS Number:
5209585
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biological source

soybean

Quality Level

type

Type IV-S

form

solid

concentration

≥30% (enzymatic)

solubility

chloroform: soluble 100 mg/mL, clear to slightly hazy, yellow to orange

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

Application

L-α-磷脂酰胆碱适用于:
  • 作为人类红细胞大量扩增培养(HEMAdef)培养基的组份,用于人成红细胞的临床扩增
  • 氯离子流出试验,检测可溶性 CLIC1 引起的脂质囊泡的氯离子渗透性
  • 测定溶解的蜡合酶活性的试验
  • 作为缓冲液 A 的组分,用于重悬腺苷酸环化酶的胆酸盐溶解催化单元
  • 作为冷冻反刍动物精子的冷冻保护剂
  • 作为评估磷脂酶活性的底物
  • 制备脂质体,评估其 ARF(ADP 核糖基化因子)和 AP-1(衔接蛋白)的募集效率
  • 制备可溶性腺苷酸环化酶的分离催化单元

Biochem/physiol Actions

磷脂酰胆碱是真核细胞中的主要膜磷脂,形成这些膜的结构组分。它还用作几种脂质信使的储库和几种生物活性脂质的来源,例如溶血磷脂酰胆碱、磷脂酸、二酰基甘油、溶血磷脂酰胆碱、血小板活化因子和花生四烯酸。
脑磷脂脑中的主要结构磷脂,包含脂肪总量的约15%;主要局限于灰质。

Preparation Note

纯化自产品 P 5638


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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

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Carlos Andres Morales Letona et al.
Polymers, 11(2) (2019-04-10)
Here, we report a facile and effective one-pot approach to prepare uniform amylose-based polymeric microparticles (PMPs) through enzymatic synthesis of short-chain amylose (SCA) followed by spontaneous self-assembly of the SCA in the presence of lecithin. The effect of lecithin on
J W Winslow et al.
The Journal of biological chemistry, 261(17), 7626-7634 (1986-06-15)
ATP analogues were used to study the active site specificity of the catalytic unit (C) of solubilized and partially purified bovine brain caudate nucleus adenylate cyclase. Phenylenediamine ATP (PD-ATP), 8-azido ATP (8-N3ATP), chromium(III) 3'-beta-alanylarylazido ATP (CrATPa), and 2',3'-dialdehyde ATP (oATP)
W Jiang et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(9), 4966-4971 (2001-04-26)
The stoichiometry of c subunits in the H(+)-transporting F(o) rotary motor of ATP synthase is uncertain, the most recent suggestions varying from 10 to 14. The stoichiometry will determine the number of H(+) transported per ATP synthesized and will directly



全球贸易项目编号

货号GTIN
P3644-100G04061834369356
P3644-25G04061835547555
P3644-1KG04061834372684
P3644-500G04061834372691