P4329
1,2-二棕榈酰-sn-甘油-3-磷酰胆碱
≥99% (TLC)
别名:
PC, (7R)-4-羟基-N,N,N-三甲基-10-氧代-7-[(1-氧代十六烷基)氧基]- 3,5,9-三氧杂-4-磷杂二十五烷-1-铵4-氧化物， 内盐, 1,2-二十六酰- 锡 -甘油基-3-磷酸胆碱, 1,2-二棕榈酰-sn-甘油-3-磷酰胆碱, 1,2-二棕榈酰- L -卵磷脂, 1,2-双十六酰基-sn-甘油-3-磷酰胆碱, L-α-磷脂酰胆碱，二棕榈酰, L-β,γ-二棕榈酰-α-卵磷脂, PC(16:0/16:0), 二棕榈酰磷脂酰胆碱
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关于此项目
经验公式（希尔记法）:
C40H80NO8P
化学文摘社编号:
分子量:
734.04
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
200-567-6
MDL number:
biological source
synthetic
Quality Level
assay
≥99% (TLC)
form
powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChI key
KILNVBDSWZSGLL-KXQOOQHDSA-N
Application
- (6)-对伞花烃钌（II）配合物对模拟癌症和健康细胞膜的Langmuir单分子膜的影响与其毒性无关。：该研究调查了钌（II）配合物与Langmuir单分子膜（包括1,2-双棕榈酰- san -甘油-3-磷酸胆碱）的相互作用，强调了癌变和健康细胞膜模型之间的行为差异（Wrobel et al., 2024）。
- 胆固醇改变模型细胞膜的界面水排列。：该研究探讨了胆固醇如何影响包括1,2-双棕榈酰-sn-甘油-3-磷酸胆碱在内的模型细胞膜界面处的水排列，为膜生物物理学提供启示（Orlikowska-Rzeznik et al., 2024）。
- 脂质组成对囊泡蛋白吸附的影响BSA案例研究。：研究了不同的脂质成分，包括1,2-双棕榈酰-sn-甘油-3-磷酸胆碱，对牛血清白蛋白在囊泡上吸附的影响，以了解蛋白质-脂质相互作用（Amarandi et al., 2024）。
- 脂筏存在时布洛芬在模型膜中的空间排列。：本文研究了布洛芬在含有脂筏和1,2-双棕榈酰-sn-甘油-3-磷酸胆碱的模型膜内的排列，揭示了药物-膜相互作用（Kashnik et al., 2024）。
Other Notes
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Johannes Thoma et al.
Chemical communications (Cambridge, England), 48(70), 8811-8813 (2012-07-28)
We present a model system to demonstrate that the positioning of biomolecules (membrane proteins) in a nonnative, complex thin film environment can be regulated by the phase behavior of film components. Partial separation between an amphiphilic polymer and a lipid
Edyta Paszko et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 202-210 (2012-11-20)
Photodynamic therapy (PDT) is based on the delivery of photocytotoxic agents to a target tissue, followed by irradiation. In order to increase the efficiency of PDT in oesophageal cancer therapy, polyethylene glycol (PEG)-grafted, transferrin (Tf)-conjugated liposome formulations of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (Foscan)
Fernando R Moya et al.
Pediatrics, 115(4), 1018-1029 (2005-04-05)
Evidence suggests that synthetic surfactants consisting solely of phospholipids can be improved through the addition of peptides, such as sinapultide, that mimic the action of human surfactant protein-B (SP-B). A synthetic surfactant containing a mimic of SP-B may also reduce
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P4329-25MG | 04061832796789 |
| P4329-100MG | 04061834374312 |
| P4329-1G | 04061826686218 |
| P4329-500MG | 04061832796796 |