P4860
蛋白酶 来源于地衣芽孢杆菌
≥2.4 U/g
别名:
Alcalase® 2.4L, Subtilisin A, Subtilisin Carslberg, 枯草杆菌蛋白酶A, 蛋白酶 来源于地衣芽孢杆菌
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
eCl@ss:
32160410
EC Number:
232-752-2
NACRES:
NA.54
MDL number:
Specific activity:
≥2.4 U/g
General description
蛋白水解酶具有催化、非催化和辅助结构域。蛋白水解酶大致分为内肽酶和外肽酶。根据功能可分为天冬氨酸、谷氨酸、半胱氨酸、苏氨酸、丝氨酸和金属蛋白酶。
Application
Sigma 公司的酶已被用于制备鸡（腿）骨蛋白水解产物，同时评估 ACE 抑制肽。在研究它们的抗肿瘤活性时，它还被用于水解蛋白核小球藻（Chlorella pyrenoidosa）蛋白质提取物。
蛋白酶是一种通过水解肽键来分解蛋白的酶。 蛋白酶用于降解蛋白质，研究蛋白酶抑制剂和研究热失活动力学。 蛋白酶用于孵育中的核酸分离步骤。
Biochem/physiol Actions
碱性蛋白酶是丝氨酸型的内切蛋白酶。它具有广泛的底物特异性，可以水解蛋白质分子中的大多数肽键。它在 pH 6.5 和 8.5 之间有活性，最适温度为 60°C。该酶可用在洗涤剂配方中，以去除蛋白质污渍。
蛋白酶通过肽键的水解使蛋白质分解代谢。 蛋白酶被丝氨酸活性位点抑制剂灭活，例如苯甲基磺酰氟（PMSF）和二异丙基氟磷酸盐。
Analysis Note
用安森单位表示的活性
Legal Information
Novozyme公司的产品
Alcalase is a registered trademark of Novozymes Corp.
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
常规特殊物品
此项目有
Fu-Yuan Cheng et al.
Animal science journal = Nihon chikusan Gakkaiho, 80(1), 91-97 (2010-02-19)
This study aims to identify peptides with angiotensin-I converting enzyme (ACE) inhibitory activity in hydrolysate from chicken leg bone protein hydrolyzed with alcalase for 4 h (A4H). The hydrolysate has demonstrated potent in vitro ACE inhibitory activity, and has been
Xiaoqin Wang et al.
Biotechnology progress, 29(3), 681-687 (2013-04-23)
Chlorella pyrenoidosa is a unicellular green algae and has been a popular foodstuff worldwide. However, no reports on the antitumor peptides from such a microalgae are available in the literature. In this study, using low-temperature high-pressure extraction, enzymatic hydrolysis, ion
Andrew R Hirst et al.
Nature chemistry, 2(12), 1089-1094 (2010-11-26)
Supramolecular gels, which demonstrate tunable functionalities, have attracted much interest in a range of areas, including healthcare, environmental protection and energy-related technologies. Preparing these materials in a reliable manner is challenging, with an increased level of kinetic defects observed at
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P4860-250ML | 04061834375272 |
| P4860-50ML | 04061838256195 |