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P5648

β-丙内酯

Name: β-丙内酯
Brand: SIGMA

Grade II, ≥90%

别名:

Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone

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关于此项目

经验公式（希尔记法）:

C₃H₄O₂

化学文摘社编号:

57-57-8

分子量:

72.06

NACRES:

NA.77

PubChem Substance ID:

24898684

UNSPSC Code:

12352103

EC Number:

200-340-1

MDL number:

MFCD00005169

Assay:

≥90%

Quality level:

200

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属性

type

Grade II

Quality Level

200

assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

O=C1CCO1

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

说明

General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

Application

β-Propiolactone has been used for Influenza virus deactivation.

Disclaimer

Insoluble polymers may form during storage.

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H315,H319,H330,H350

pcodes

P202 - P260 - P264 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Platelets Modulate Innate Immune Response Against Human Respiratory Syncytial Virus In Vitro.

Vesla I Kullaya et al.

Viral immunology, 30(8), 576-581 (2017-08-08)

Detection of respiratory syncytial virus (RSV) in blood, including mononuclear leukocytes and organs other than the lung, suggests that RSV disseminates outside the respiratory tract. In this study, the role of platelets in host defense against RSV was explored using

Veterinary Immunology-E book, 262-262 (2013)

The Optimal Concentration of Formaldehyde is Key to Stabilizing the Pre-Fusion Conformation of Respiratory Syncytial Virus Fusion Protein.

Wei Zhang et al.

Viruses, 11(7) (2019-07-11)

To date, there is no licensed vaccine available to prevent respiratory syncytial virus (RSV) infection. The valuable pre-fusion conformation of the fusion protein (pre-F) is prone to lose high neutralizing antigenic sites. The goals of this study were to stabilize

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全球贸易项目编号

货号	GTIN
P5648-10ML	04061838164629
P5648-100ML	04061838164612
P5648-1ML	04061838164636
P5648-50ML	04061838114556
P5648-5ML	04061838092823